Smoking, antioxidant supplementation and dietary intakes among older adults with age-related macular degeneration over 10 years.
Smoking, antioxidant supplementation and dietary intakes among older adults with age-related macular degeneration over 10 years.
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DOI：
10.1371/journal.pone.0122548
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Mitchell P
中科院分区：
文献类型：
--
作者：
Gopinath B;Flood VM;Kifley A;Liew G;Mitchell P
我们的目的是比较10年内患有和不患有年龄相关性黄斑变性（AMD）的人的微量营养素使用和其他生活方式行为。1612名基线时年龄在49岁以上的参与者在澳大利亚悉尼西部接受了10年的重新检查。根据视网膜照片评估AMD。饮食数据收集使用半定量的食物频率问卷。吸烟状态是自我报告的。56名参与者在基线时患有任何AMD，其中25%在5年时戒烟，并且在10年随访时仍然不吸烟。在基线时维生素A、C或E补充剂摄入量低于推荐摄入量的参与者中，与10年内未发生晚期AMD的参与者相比，10年随访时维生素A（总）、C或E补充剂摄入量高于推荐摄入量的参与者更有可能报告：多变量调整OR 4.21（95% CI 1.65-10.73）; OR 6.52（95% CI 2.76-15.41）;和OR 5.71（95% CI 2.42-13.51）。与没有AMD的参与者相比，没有明显增加鱼类，水果和蔬菜的消费量以及整体饮食质量。老年AMD患者对吸烟和饮食建议的依从性较差。然而，抗氧化剂补充剂的摄取在晚期AMD患者中显着增加。
We aimed to compare the micronutrient usage and other lifestyle behaviors over 10 years among those with and without age-related macular degeneration (AMD). 1612 participants aged 49+ years at baseline were re-examined over 10 years, west of Sydney, Australia. AMD was assessed from retinal photographs. Dietary data were collected using a semi-quantitative food frequency questionnaire. Smoking status was self-reported. 56 participants had any AMD at baseline, of these 25% quit smoking at 5 years and were still not smoking at 10-year follow-up. Among participants who had below the recommended intake of vitamins A, C or E supplements at baseline, those who did compared to those who did not develop late AMD over 10 years were more likely to report vitamins A (total), C or E supplement intake above the recommended intake at 10-year follow-up: multivariable-adjusted OR 4.21 (95% CI 1.65-10.73); OR 6.52 (95% CI 2.76-15.41); and OR 5.71 (95% CI 2.42-13.51), respectively. Participants with compared to without AMD did not appreciably increase fish, fruit and vegetable consumption and overall diet quality. Adherence to smoking and dietary recommendations was poor among older adults with AMD. However, uptake of antioxidant supplements increased significantly among those with late AMD.
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影响因子：
13.7
作者：
Mitchell, P;Wang, JJ;Smith, W
通讯作者：
Smith, W
影响因子：
--
作者：
Kassoff, A;Kassoff, J;Chew, EY
通讯作者：
Chew, EY
影响因子：
7.1
作者：
Kaushik, Shweta;Wang, Jie Jin;Mitchell, Paul
通讯作者：
Mitchell, Paul
澳大利亚“失明”烟草警告标签的积极影响：ITC四个国家调查的发现。
影响因子：
1.9
作者：
Kennedy RD;Spafford MM;Behm I;Hammond D;Fong GT;Borland R
通讯作者：
Borland R
影响因子：
3.2
作者：
Barclay, Alan Winston;Flood, Victoria Mary;Mitchell, Paul
通讯作者：
Mitchell, Paul