The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases.

The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases.
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DOI:
10.1093/nar/gkt1115
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发表时间:
2014-01
影响因子:
14.9
通讯作者:
Hermjakob H
Hermjakob H
中科院分区:
生物学2区
文献类型:
--
作者:
Orchard S;Ammari M;Aranda B;Breuza L;Briganti L;Broackes-Carter F;Campbell NH;Chavali G;Chen C;del-Toro N;Duesbury M;Dumousseau M;Galeota E;Hinz U;Iannuccelli M;Jagannathan S;Jimenez R;Khadake J;Lagreid A;Licata L;Lovering RC;Meldal B;Melidoni AN;Milagros M;Peluso D;Perfetto L;Porras P;Raghunath A;Ricard-Blum S;Roechert B;Stutz A;Tognolli M;van Roey K;Cesareni G;Hermjakob H

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IntAct(可在http://www.ebi.ac.uk/intact上免费获得)是一个开源、开放数据的分子相互作用数据库,由文献或直接数据沉积中的数据填充。IntAct开发了一个复杂的基于Web的策展工具,能够支持IMEx和MIMix级别的策展。这个工具现在被多个额外的策展团队使用,他们都将数据直接注释到IntAct数据库中。IntAct团队的成员提供适当水平的培训,对条目进行质量控制,并负责长期的数据维护。最近,MINT和IntAct数据库决定合并它们各自的工作,以最佳地利用有限的开发人员资源并最大限度地提高策展产出。由MINT管理员手动管理的所有数据已被转移到EMBL-EBI的IntAct数据库中,并与现有的IntAct数据集合并。IntAct和MINT都是IMEx联盟(http://www.example.com)的积极贡献者。www.imexconsortium.org
IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org).
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