Diagnosis of axillary lymph node metastases in patients with breast cancer
Diagnosis of axillary lymph node metastases in patients with breast cancer
复制标题
乳腺癌患者腋窝淋巴结转移的诊断
DOI：
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发表时间：
2005
影响因子：
3.8
通讯作者：
I. Miyazaki
中科院分区：
文献类型：
--
作者：
M. Noguchi;N. Katev;I. Miyazaki
乳腺癌腋窝（AX）转移的诊断仍然是乳腺癌治疗中的一个挑战，也是一个有争议的话题。临床淋巴结分期在AX淋巴结的评估中显然是有限的。AX乳腺X线摄影、超声检查和计算机断层扫描（CT）不能提供组织学信息。虽然核磁共振成像可能有相当大的价值，在诊断AX转移，它不能检测微转移。生物学标记物在AX转移评估中的应用仍是一个研究课题。另一方面，对选定的AX淋巴结或组织进行活检并进行组织学或细胞学检查，通常不会识别出显著百分比的AX淋巴结受累患者。前哨淋巴结活检，然而，可能是潜在的有用的评估AX转移，虽然它仍然是研究。为了简化诊断和降低发病率和死亡率，必须寻求AX夹层的替代方法，并改进成像和分期方式。我们对乳腺癌患者AX转移诊断的相关文献进行了回顾，并对目前存在争议的一些领域进行了讨论。
SummaryThe diagnosis of axillary (AX) metastases remains a challenge in the management of breast cancer and is a subject of controversy. Clinical node staging clearly is limited in the assessment of AX lymph nodes. AX mammography, ultrasonography, and computed tomography (CT) do not provide histologic information. Although nuclear magnetic resonance imaging may have considerable value in the diagnosis of AX metastases, it does not detect micrometastases. The use of biologic markers in the assessment of AX metastases remains a subject of investigation. On the other hand, biopsy of selected AX nodes or tissue with examination of histology or cytology generally would not identify a significant percentage of patients with AX node involvement. Sentinel lymph node biopsy, however, might be potentially useful for assessing AX metastases, although it remains investigational. In order to simplify diagnosis and reduce morbidity and mortality, alternatives to AX dissection must be sought and imaging and staging modalities refined. We present a review of the literature pertaining to the diagnosis of AX metastases in patients with breast cancer and a discussion of some current areas of controversy.
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影响因子：
11.2
作者：
H. Oka;H. Shiozaki;K. Kobayashi;M. Inoue;H. Tahara;Tetsurou Kobayashi;Y. Takatsuka;N. Matsuyoshi;S. Hirano;M. Takeichi;T. Mori
通讯作者：
H. Oka;H. Shiozaki;K. Kobayashi;M. Inoue;H. Tahara;Tetsurou Kobayashi;Y. Takatsuka;N. Matsuyoshi;S. Hirano;M. Takeichi;T. Mori
影响因子：
158.5
作者：
FISHER, B;REDMOND, C;FOSTER, R
通讯作者：
FOSTER, R
影响因子：
158.5
作者：
FISHER, B;BAUER, M;RUSSELL, I
通讯作者：
RUSSELL, I
影响因子：
10.3
作者：
STEEG, PS;BEVILACQUA, G;SOBEL, ME
通讯作者：
SOBEL, ME