The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas.
The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas.
复制标题
DOI:
10.1016/j.neuron.2017.10.007
复制
发表时间:
2017-11-01
期刊:
影响因子:
16.2
通讯作者:
Zeng H
中科院分区:
文献类型:
--
作者:
Ecker JR;Geschwind DH;Kriegstein AR;Ngai J;Osten P;Polioudakis D;Regev A;Sestan N;Wickersham IR;Zeng H
A comprehensive characterization of neuronal cell types, their distributions and patterns of connectivity is critical for understanding the properties of neural circuits and how they generate behaviors. Here we review the experiences of the BRAIN Initiative Cell Census Consortium – ten pilot projects funded by the U.S. BRAIN Initiative – in developing, validating and scaling up emerging genomic and anatomical mapping technologies for creating a complete inventory of neuronal cell types and their connections in multiple species and during development. These projects lay the foundation for a larger and longer-term effort to generate whole-brain cell atlases in species including mice and humans. In this Perspective, Ecker et al. discuss the efforts of the BRAIN Initiative Cell Census Consortium, ten pilot projects whose collective goal was to develop and validate methods for generating comprehensive atlases of neuronal cell types in the mammalian brain.
登录
查看更多内容
影响因子:
5.7
作者:
Bandler RC;Mayer C;Fishell G
通讯作者:
Fishell G
影响因子:
11
作者:
Bardy, C.;van den Hurk, M.;Kakaradov, B.;Erwin, J. A.;Jaeger, B. N.;Hernandez, R. V.;Eames, T.;Paucar, A. A.;Gorris, M.;Marchand, C.;Jappelli, R.;Barron, J.;Bryant, A. K.;Kellogg, M.;Lasken, R. S.;Rutten, B. P. F.;Steinbusch, H. W. M.;Yeo, G. W.;Gage, F. H.
通讯作者:
Gage, F. H.
影响因子:
25
作者:
Chan KY;Jang MJ;Yoo BB;Greenbaum A;Ravi N;Wu WL;Sánchez-Guardado L;Lois C;Mazmanian SK;Deverman BE;Gradinaru V
通讯作者:
Gradinaru V
影响因子:
46.9
作者:
Cadwell CR;Palasantza A;Jiang X;Berens P;Deng Q;Yilmaz M;Reimer J;Shen S;Bethge M;Tolias KF;Sandberg R;Tolias AS
通讯作者:
Tolias AS
DOI:
10.1073/pnas.0509032102
发表时间:
2005-12-06
影响因子:
11.1
作者:
Chen, JG;Rasin, MR;Sestan, N
通讯作者:
Sestan, N