Associations between the Severity of Sarcopenia and Health-Related Quality of Life in Community-Dwelling Middle-Aged and Older Adults.
Associations between the Severity of Sarcopenia and Health-Related Quality of Life in Community-Dwelling Middle-Aged and Older Adults.
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社区居住中老年人肌肉减少症严重程度与健康相关生活质量之间的关系
DOI：
10.3390/ijerph18158026
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发表时间：
2021-07-29
影响因子：
--
通讯作者：
Aibar-Almazán A
中科院分区：
文献类型：
--
作者：
Fábrega-Cuadros R;Hita-Contreras F;Martínez-Amat A;Jiménez-García JD;Achalandabaso-Ochoa A;Lavilla-Lerma L;García-Garro PA;Álvarez-Salvago F;Aibar-Almazán A
(1)研究背景：本研究的目的是分析社区中老年人骨质疏松症的严重程度与健康相关生活质量之间的关系。(2)方法：采用横断面研究方法，通过测量肌力(握力测力仪)、肌肉质量(生物电阻抗分析)和体能(计时起跳试验)，对304名老年受试者进行骨质疏松症的严重程度评估。采用通用36项简明健康调查问卷(SF-36)对患者的生活质量进行评估。焦虑和抑郁(医院焦虑和抑郁量表)以及年龄被认为是可能的混杂因素。可能的骨量减少是由低肌力确定的；确认的骨量减少是由肌肉力量和肌肉质量降低的存在定义的；严重的骨量减少是由肌肉力量和质量降低以及身体表现不佳定义的。(3)线性回归分析显示，可能存在的骨质疏松症与SF-36的生理作用(调整后R2=0.183)、一般健康(调整后R2=0.290)和社会功能(调整后R2=0.299)有关。至于SF-36的心理(MCS)和身体(PCS)部分总分，可能的骨质疏松症以及抑郁和焦虑仍然与MCS相关(调整后的R2=0.518)，这三个变量以及年龄与PCS相关(调整后的R2=0.340)。(4)结论：可能的骨质疏松症，但没有确诊的或严重的骨质疏松症，独立地与较差的HRQOL相关。更准确地说，它与PCS和MCS有关，也与SF-36领域的身体作用、一般健康和社会功能有关。
(1) Background: The aim of this study was to analyze the associations between severity of sarcopenia and health-related quality of life (HRQoL) among community-dwelling middle-aged and older adults. (2) Methods: A cross-sectional study involving 304 older-adult participants was used to assess the severity of sarcopenia by measuring muscle strength (handgrip dynamometer), muscle mass (bioelectrical impedance analysis), and physical performance (Timed Up-and-Go test). The generic 36-item Short-Form Health Survey (SF-36) was used to evaluate HRQoL. Anxiety and depression (Hospital Anxiety and Depression Scale) as well as age were considered as possible confounders. Probable sarcopenia was determined by low muscle strength; confirmed sarcopenia was defined by the presence of both low muscle strength and muscle mass; and severe sarcopenia was defined by low muscle strength and mass along with poor physical performance. (3) Results: The linear regression analysis showed that the presence of probable sarcopenia was associated with the SF-36 domains physical role (adjusted R2 = 0.183), general health (adjusted R2 = 0.290), and social functioning (adjusted R2 = 0.299). As for the SF-36 mental (MCS) and physical (PCS) component summary scores, probable sarcopenia, as well as depression and anxiety, remained associated with MCS (adjusted R2 = 0.518), and these three variables, together with age, were linked to PCS (adjusted R2 = 0.340). (4) Conclusions: Probable sarcopenia, but not confirmed or severe sarcopenia, was independently associated with poor HRQoL. More precisely, it was related to PCS and MCS, as well as to the physical role, general health, and social functioning of SF-36 domains.
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影响因子：
2.5
作者：
Kull, Mart;Kallikorm, Riina;Lember, Margus
通讯作者：
Lember, Margus
影响因子：
2.3
作者：
Go, Seon Won;Cha, Young Hwa;Park, Hye Soon
通讯作者：
Park, Hye Soon
影响因子：
3.3
作者：
Janssen, I;Heymsfield, SB;Ross, R
通讯作者：
Ross, R
DOI：
10.3390/ijerph16183275
发表时间：
2019-09-02
影响因子：
--
作者：
Castillo-Olea, Cristian;Garcia-Zapirain Soto, Begonya;Zuniga, Clemente
通讯作者：
Zuniga, Clemente
影响因子：
4.5
作者：
Cho, Yoonsu;Shin, So-Youn;Shin, Min-Jeong
通讯作者：
Shin, Min-Jeong