Visceral fat and cardiorespiratory fitness with prevalence of pre-diabetes/diabetes mellitus among middle-aged and elderly Japanese people: WASEDA'S Health Study.
Visceral fat and cardiorespiratory fitness with prevalence of pre-diabetes/diabetes mellitus among middle-aged and elderly Japanese people: WASEDA'S Health Study.
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DOI：
10.1371/journal.pone.0241018
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发表时间：
2020
期刊：
影响因子：
3.7
通讯作者：
Higuchi M
中科院分区：
文献类型：
--
作者：
Usui C;Kawakami R;Tanisawa K;Ito T;Tabata H;Iizuka S;Kawamura T;Midorikawa T;Sawada SS;Torii S;Sakamoto S;Suzuki K;Ishii K;Oka K;Muraoka I;Higuchi M
不受肥胖混淆的心肺适能（CRF）测量结果与糖尿病前期（pre-DM）和糖尿病（DM）患病率之间的关系尚不清楚。因此，我们的目的是调查内脏脂肪（VF）和CRF与日本成年人糖尿病前期/糖尿病患病率的关系。该研究包括970名40-87岁的人（327名女性和643名男性），他们在2015-2018年期间进行了完整的健康检查，腹部脂肪面积和WASEDA健康研究的健身数据。使用磁共振成像测量VF面积。使用自行车测力计测量CRF，并将其定义为VO 2峰值除以无脂肪质量。根据问卷调查和空腹血液检查确定糖尿病前期/糖尿病。计算糖尿病前期/糖尿病患病率的比值比（OR）和95%置信区间（CI）。73名参与者患有糖尿病前期，48名参与者患有糖尿病。与低VF组相比，高VF组有更高的糖尿病前期/糖尿病患病率（OR：1.87，95%CI：1.18-2.96），尽管CRF与糖尿病前期/糖尿病患病率之间没有观察到显著相关性（趋势P = 0.239）。亚组分析还显示，在低VF组中，CRF与糖尿病前期/糖尿病患病率之间无显著关系（趋势P = 0.979），尽管在高VF组中，CRF值与糖尿病前期/糖尿病患病率呈负相关（趋势P = 0.024）。虽然CRF与肥胖校正后的糖尿病前期/糖尿病患病率无独立相关性，但VF值越高，糖尿病前期/糖尿病患病率越高。此外，CRF水平与糖尿病前期/糖尿病的患病率呈负相关，仅在高VF个体中。
The relationships between cardiorespiratory fitness (CRF) measurements not confounded by adiposity and the prevalence of pre-diabetes mellitus (pre-DM) and diabetes mellitus (DM) are not well known. Thus, we aimed to investigate the associations of visceral fat (VF) and CRF with the prevalence of pre-DM/DM among Japanese adults. The study included 970 individuals (327 women and 643 men) who were 40–87 years old and had complete health examinations, abdominal fat area, and fitness data from WASEDA’S Health Study during 2015–2018. The VF area was measured using magnetic resonance imaging. CRF was measured using a cycle ergometer and was defined as VO2peak divided by fat free mass. The pre-DM/DM was identified based on the questionnaire and fasting blood tests. The odds ratios (ORs) and 95% confidence intervals (CIs) for prevalence of pre-DM/DM were calculated. Seventy-three participants had pre-DM and 48 participants had DM. Compared to the low VF group, the high VF group had a higher prevalence of pre-DM/DM (OR: 1.87, 95% CI: 1.18–2.96), although no significant relationship was observed between CRF and pre-DM/DM prevalence (P for trend = 0.239). The sub-group analyses also revealed no significant relationship between CRF and pre-DM/DM prevalence in the low VF group (P for trend = 0.979), although CRF values were inversely related to the prevalence of pre-DM/DM in the high VF group (P for trend = 0.024). Although CRF was not independently related to the prevalence of pre-DM/DM after adjusting for adiposity, higher VF values were related to a higher prevalence of pre-DM/DM. In addition, CRF levels were inversely associated with the prevalence of pre-DM/DM only among high VF individuals.
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影响因子：
4.7
作者：
Kawakami R;Sawada SS;Lee IM;Gando Y;Momma H;Terada S;Kinugawa C;Okamoto T;Tsukamoto K;Higuchi M;Miyachi M;Blair SN
通讯作者：
Blair SN
影响因子：
7.9
作者：
Karastergiou K;Smith SR;Greenberg AS;Fried SK
通讯作者：
Fried SK
影响因子：
5.8
作者：
Granados, Andrea;Gebremariam, Achamyeleh;Lee, Joyce M.
通讯作者：
Lee, Joyce M.
DOI：
10.1249/mss.0000000000002289
发表时间：
2020-07-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Imboden, Mary T.;Kaminsky, Leonard A.;Harber, Matthew P.
通讯作者：
Harber, Matthew P.
影响因子：
3.4
作者：
Huth, Claire;Pigeon, Etienne;Joanisse, Denis R.
通讯作者：
Joanisse, Denis R.