Sickness and the Social Brain: Love in the Time of COVID.
Sickness and the Social Brain: Love in the Time of COVID.
复制标题
疾病与社会大脑：新冠肺炎时期的爱
DOI：
10.3389/fpsyt.2021.633664
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发表时间：
2021
影响因子：
4.7
通讯作者：
Bilbo SD
中科院分区：
文献类型：
--
作者：
Smith CJ;Bilbo SD
作为一个高度社会化的物种，融入社交网络和强大的社会纽带对我们的健康和福祉至关重要。事实上，受损的社会功能是许多神经精神障碍的组成部分，包括抑郁症，焦虑症和物质使用障碍。在当前的COVID-19疫情期间，我们的社交网络面临断裂的风险，许多人容易受到社交孤立的负面影响。重要的是，感染本身会导致社会行为的变化，这是“疾病行为”的一个组成部分。此外，与COVID-19的情况一样，男性和女性对感染的免疫反应往往不同，因此对负面结果的敏感性也不同。在这篇综述中，我们讨论了感染改变社会行为的许多方式，有时是为了宿主的利益，有时是为了病原体，从真社会性昆虫到人类。我们还探讨了这些社会行为变化发生的神经免疫机制。最后，我们触及的方式，社会环境（群体生活，社会隔离等）。塑造免疫系统及其应对挑战的能力。在整个过程中，我们强调如何男性和女性不同，在他们的免疫激活反应，无论是行为和生理。
As a highly social species, inclusion in social networks and the presence of strong social bonds are critical to our health and well-being. Indeed, impaired social functioning is a component of numerous neuropsychiatric disorders including depression, anxiety, and substance use disorder. During the current COVID-19 pandemic, our social networks are at risk of fracture and many are vulnerable to the negative consequences of social isolation. Importantly, infection itself leads to changes in social behavior as a component of “sickness behavior.” Furthermore, as in the case of COVID-19, males and females often differ in their immunological response to infection, and, therefore, in their susceptibility to negative outcomes. In this review, we discuss the many ways in which infection changes social behavior—sometimes to the benefit of the host, and in some instances for the sake of the pathogen—in species ranging from eusocial insects to humans. We also explore the neuroimmune mechanisms by which these changes in social behavior occur. Finally, we touch upon the ways in which the social environment (group living, social isolation, etc.) shapes the immune system and its ability to respond to challenge. Throughout we emphasize how males and females differ in their response to immune activation, both behaviorally and physiologically.
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影响因子：
3.5
作者：
Bilbo, Staci D.
通讯作者：
Bilbo, Staci D.
影响因子：
4.2
作者：
Buttini, M;Limonta, S;Boddeke, HWGM
通讯作者：
Boddeke, HWGM
影响因子：
3.7
作者：
BLUTHE, RM;PAWLOWSKI, M;DANTZER, R
通讯作者：
DANTZER, R
影响因子：
2.4
作者：
Boos, Stefan;Meunier, Joel;Koelliker, Mathias
通讯作者：
Koelliker, Mathias
DOI：
10.1111/j.1749-6632.2010.05445.x
发表时间：
2010-01-01
期刊：
YEAR IN COGNITIVE NEUROSCIENCE 2010
影响因子：
--
作者：
Adolphs, Ralph
通讯作者：
Adolphs, Ralph