Panax Ginseng C.A.Mey. as Medicine: The Potential Use of Panax Ginseng C.A.Mey. as a Remedy for Kidney Protection from a Pharmacological Perspective.
Panax Ginseng C.A.Mey. as Medicine: The Potential Use of Panax Ginseng C.A.Mey. as a Remedy for Kidney Protection from a Pharmacological Perspective.
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DOI：
10.3389/fphar.2021.734151
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发表时间：
2021
影响因子：
5.6
通讯作者：
Tong X
中科院分区：
文献类型：
--
作者：
Jin D;Zhang Y;Zhang Y;Duan L;Zhou R;Duan Y;Sun Y;Lian F;Tong X
人参 C.A.Mey.作为天然来源的食品/膳食补充剂已被广泛消费，其治疗特性也引起了广泛关注。人参 C.A.Mey 的治疗特性。抗炎、改善慢性炎症、增强免疫力、抗氧化、调节糖脂代谢等作用已被广泛报道。近年来，许多有趣的研究报道了人参 C.A.Mey 的潜在用途。在 DKD 的管理中。 DKD 已成为全球终末期肾病的主要原因，这增加了过早死亡的风险并造成严重的经济负担。尽管 DKD 在某种程度上可以通过血管紧张素转换酶抑制剂 (ACEI)、血管紧张素受体阻滞剂 (ARB) 和降血糖药物等不同药物进行控制，但与 DKD 相关的现代饮食变化促进了研究，以评估天然来源的膳食补充剂作为药物（包括人参 C.A.Mey）的预防和治疗优点。许多科学证据的结果表明，人参 C.A.Mey.可以缓解DKD细胞和动物模型的病理状态。此外，一些研究表明，应用或食用人参C.A.Mey后，DKD患者的临床表型可得到缓解，如降低蛋白尿、血清肌酐和肾性贫血。因此，本综述旨在讨论人参C.A.Mey的有效性。从药理学角度作为针对 DKD 病理表型的药物。这篇综述将为人们了解人参 C.A.Mey 的潜在用途提供新的见解。临床环境中 DKD 的管理。
Panax ginseng C.A.Mey. has been widely consumed as food/diet supplements from natural sources, and its therapeutic properties have also aroused widespread concern. Therapeutic properties of Panax ginseng C.A.Mey. such as anti-inflammatory, ameliorating chronic inflammation, enhancing the immunity, resisting the oxidation again, and regulating the glucose and lipid metabolism have been widely reported. Recent years, lots of interesting studies have reported the potential use of Panax ginseng C.A.Mey. in the management of DKD. DKD has become the leading cause of end-stage renal disease worldwide, which increases the risk of premature death and poses a serious financial burden. Although DKD is somehow controllable with different drugs such as Angiotensin-Converting Enzyme Inhibitors (ACEI), Angiotensin Receptor Blockers (ARB) and lowering-glucose agents, modern dietary changes associated with DKD have facilitated research to assess the preventive and therapeutic merits of diet supplements from natural sources as medicine including Panax ginseng C.A.Mey. Findings from many scientific evidences have suggested that Panax ginseng C.A.Mey. can relieve the pathological status in cellular and animal models of DKD. Moreover, a few studies showed that alleviation of clinical phenotype such as reducing albuminuria, serum creatinine and renal anemia in DKD patients after application or consumption of Panax ginseng C.A.Mey.. Therefore, this review aims to discuss the effectiveness of Panax ginseng C.A.Mey. as medicine for targeting pathological phenotypes in DKD from a pharmacological perspective. This review will provide new insights into the potential understanding use of Panax ginseng C.A.Mey. in the management of DKD in clinical settings.
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DOI：
10.1038/s41581-018-0103-6
发表时间：
2019-04
期刊：
Nature reviews. Nephrology
影响因子：
--
作者：
Guo C;Dong G;Liang X;Dong Z
通讯作者：
Dong Z
影响因子：
13.1
作者：
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影响因子：
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作者：
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影响因子：
6.3
作者：
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DOI：
10.3109/21691401.2013.794358
发表时间：
2014-06-01
影响因子：
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作者：
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