A Behavioral Lifestyle Intervention to Limit Gestational Weight Gain in Pregnant Women with Overweight and Obesity.

A Behavioral Lifestyle Intervention to Limit Gestational Weight Gain in Pregnant Women with Overweight and Obesity.
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限制超重和肥胖孕妇妊娠期体重增加的行为生活方式干预。

DOI:
10.1002/oby.23119
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发表时间:
2021-04
期刊:
Obesity (Silver Spring, Md.)
影响因子:
--
通讯作者:
--
中科院分区:
其他
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本研究旨在评估产前行为生活方式干预对总孕期体重增加(GWG)和围产儿结局的影响。南卡罗来纳州超重和肥胖的孕妇被招募到一项基于理论的随机对照试验(n=112干预,n=105标准护理),该试验旨在针对体重自我监测、增加体力活动和改善饮食习惯。参与者是种族/民族多元化(44%的非裔美国人)。干预组和标准护理组分娩时GWG总分相似(分别为12.9±6.9和12.4±8.3 kg),但干预组GWG总分标准差较小(P=0.04)。治疗效果受到种族/民族和孕前体重指数的影响。在超重的非裔美国人参与者中,干预参与者的体重增加了4.5公斤,而在肥胖的非裔美国女性中,干预参与者比标准护理参与者增加了4.1公斤。白人参与者的总体GWG相似,无论体重状况和分组情况如何。干预参与者的不良妊娠结局少于标准护理参与者(P≤0.0 1)。行为生活方式干预对超重的非裔美国人参与者的GWG有积极影响,但对肥胖的非裔美国人参与者没有影响。干预措施对围产儿结局的总体有利影响表明,GWG总和以外的机制可能推动了这些结局。
This study aimed to evaluate the effects of an antenatal behavioral lifestyle intervention on total gestational weight gain (GWG) and perinatal outcomes. Pregnant women with overweight and obesity in South Carolina were recruited into a theory-based randomized controlled trial (n = 112 intervention, n = 105 standard care), which was designed to target weight self-monitoring, increased physical activity, and improved dietary practices. Participants were racially/ethnically diverse (44% African American). Intervention and standard care participants had similar total GWG at delivery (12.9 ± 6.9 vs. 12.4 ± 8.3 kg, respectively), but intervention participants had a smaller standard deviation (P = 0.04) in total GWG. The treatment effects were moderated by race/ethnicity and prepregnancy BMI. Among African American participants with overweight, intervention participants gained 4.5 kg less, whereas, among African American women with obesity, intervention participants gained 4.1 kg more than standard care participants. Total GWG among White participants was similar regardless of weight status and group assignment. Fewer intervention participants than standard care participants had adverse pregnancy outcomes (P ≤ 0.01). The behavioral lifestyle intervention favorably impacted GWG in African American participants with overweight but not African American participants with obesity. The intervention’s overall favorable impact on perinatal outcomes suggests that the mechanisms beyond total GWG may drive these outcomes.
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