Diversity of full-length subtype E HIV type 1 env sequences in early seroconvertors from northern Thailand.

Diversity of full-length subtype E HIV type 1 env sequences in early seroconvertors from northern Thailand.
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泰国北部早期血清转化者中全长 E 亚型 HIV 1 型 env 序列的多样性。

DOI:
10.1089/aid.1997.13.1439
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发表时间:
1997
期刊:
AIDS research and human retroviruses.
影响因子:
--
通讯作者:
Nelson,K
Nelson,K
中科院分区:
--
文献类型:
--
作者:
Yu,XF;Wang,Z;Beyrer,C;Celentano,DD;Khamboonruang,C;Nelson,K

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已从泰国的感染者中鉴定出HIV-1的两种主要亚型,B和E。1,2泰国的HIV-1主要通过异性接触传播,3,4和E亚型HIV-1是目前在泰国传播的主要病毒。5一种基于原型亚型E病毒CM 235的Env序列的亚单位疫苗试验预计将于今年开始。6关于目前在一般人群中传播的HIV-1病毒株,特别是在最近感染的个人中传播的HIV-1病毒株的信息,对于疫苗的设计和评价至关重要。
Twomajor subtypes of HIV-1, B and E, have been identified from infected individuals in Thailand. 1, 2 HIV-1 in Thailand is mainly transmitted through heterosexual contact, 3, 4 and subtype E HIV-1 is the predominant virus currently circu-lating in Thailand. 5 A subunit vaccine trial based on the Env sequence of the prototype subtype E virus, CM235, is expected to begin this year. 6 Information regarding HIV-1 strains that are currently circulating in the general population, especially in recently infected individuals, will be critical for vaccine design and evaluation.
DOI: 10.1016/s0140-6736(94)90990-3
发表时间: 1994-01-22
期刊: LANCET
影响因子: 168.9
作者:
MASTRO, TD;SATTEN, GA;LOGINI, IM
通讯作者: LOGINI, IM
DOI: 10.1128/jvi.69.1.263-271.1995
发表时间: 1995-01-01
影响因子: 5.4
作者:
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通讯作者: BURKE, DS