Photoacoustic tomography with a single detector in a reverberant cavity.
Photoacoustic tomography with a single detector in a reverberant cavity.
复制标题
在混响腔中使用单个探测器进行光声断层扫描。
DOI：
10.1121/1.3068445
复制
发表时间：
2008
期刊：
影响因子：
--
通讯作者：
P. Beard
中科院分区：
文献类型：
--
作者：
B. Cox;P. Beard
在传统的生物医学光声层析成像（PAT）中，通过近红外光的纳秒脉冲的吸收产生的超声脉冲被记录在检测器阵列上，并用于恢复软组织内的初始声压分布的图像。该图像与组织光学系数相关，因此携带关于组织生理学的信息。对于高分辨率成像，需要具有高密度的小敏感元件的大面积探测器阵列。这样的阵列可能是昂贵的，因此混响场PAT已被建议作为使用具有较少数量的检测器的阵列来获得PAT图像的手段。通过记录来自围绕样品的声学混响腔的反射，除了主声脉冲之外，还可以捕获足够的信息以允许在不需要大面积阵列的情况下重建图像。使用二维模拟进行了初步研究，以评估使用单个探测器进行PAT的可行性。结果表明，混响场的数据记录在一个单一的检测器是足够的重建的初始压力分布准确，只要形状的混响腔，使其射线混沌。这种方法的光声成像的实用性进行了讨论。
In conventional biomedical photoacoustic tomography (PAT), ultrasonic pulses generated through the absorption of nanosecond pulses of near-infrared light are recorded over an array of detectors and used to recover an image of the initial acoustic pressure distribution within soft tissue. This image is related to the tissue optical coefficients and therefore carries information about the tissue physiology. For high resolution imaging, a large-area detector array with a high density of small, sensitive elements is required. Such arrays can be expensive, so reverberant-field PAT has been suggested as a means of obtaining PAT images using arrays with a smaller number of detectors. By recording the reflections from an acoustically reverberant cavity surrounding the sample, in addition to the primary acoustic pulse, sufficient information may be captured to allow an image to be reconstructed without the need for a large-area array. An initial study using two-dimensional simulations was performed to assess the feasibility of using a single detector for PAT. It is shown that reverberant-field data recorded at a single detector are sufficient to reconstruct the initial pressure distribution accurately, so long as the shape of the reverberant cavity makes it ray-chaotic. The practicalities of such an approach to photoacoustic imaging are discussed.
DOI：
10.1088/1751-8113/40/50/r01
发表时间：
2007-11
期刊：
Journal of Physics A: Mathematical and Theoretical
影响因子：
--
作者：
G. Tanner;N. Søndergaard
通讯作者：
G. Tanner;N. Søndergaard
从多波长光声图像同时估计发色团浓度和散射分布
DOI：
10.1117/12.762924
发表时间：
2008
期刊：
--
影响因子：
--
作者：
Cox B
通讯作者：
Cox B
影响因子：
2.8
作者：
Kruger, Robert A;Kiser, William L;Miller, Kathy D
通讯作者：
Miller, Kathy D