Resting TcPO2 levels decrease during liner wear in persons with a transtibial amputation.

Resting TcPO2 levels decrease during liner wear in persons with a transtibial amputation.
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DOI:
10.1371/journal.pone.0239930
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发表时间:
2020
期刊:
影响因子:
3.7
通讯作者:
Waibel FWA
Waibel FWA
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Berli MC;Jundt-Ecker M;Meier MR;Hofer M;Schöni M;Götschi T;Uçkay I;Böni T;Waibel FWA

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在我们的诊所中,大量患者出现无特定躯体起源的经胫骨残肢疼痛。硅胶内衬引起的组织压缩可能会减少血流量,可能导致残肢疼痛。因此,作为第一步,我们研究了内衬本身是否对经皮氧分压 (TcPO2) 产生影响。包括单侧经胫骨截肢和不明原因残肢疼痛的患者。记录病史,包括残肢疼痛,并给予 SF-36。使用两个传感器在仰卧位且不使用衬垫的情况下在 0、10、20 和 30 分钟测量静息 TcPO2 水平:一个传感器放置在胫骨末端 (= TTE) 尖端上方的横向平面中,另一个放置在腓骨室远端上方的矢状平面中 (= SPC)。使用专门准备的衬里重复测量,避免由于传感器放置而产生额外压力。使用SPSS进行统计分析。 20 人(9 名女性,11 名男性)参加,平均年龄为 68.65 岁(范围 47-86 岁)。经胫骨截肢平均发生在研究开始前 43 个月(范围 3-119 个月)。在有衬里磨损的情况下,10、20 和 30 分钟后,两个传感器测得的 TcPO2 水平均显着低于没有衬里时测量的水平(TTE:p < 0.001;SPC:p = 0.002)。随着时间的推移,传感器之间的 TcPO2 水平没有发现显着差异。 TcPO2 水平与疼痛、吸烟状况、年龄、日常使用内衬的持续时间、活动水平和翻修历史之间没有显着相关性。当仅佩戴内衬而不使用假肢接受腔时,静息 TcPO2 水平显着下降。需要进一步研究来调查衬垫磨损对运动 TcPO2 水平的影响。
In our clinic, a substantial number of patients present with transtibial residual limb pain of no specific somatic origin. Silicone liner induced tissue compression may reduce blood flow, possibly causing residual limb pain. Thus, as a first step we investigated if the liner itself has an effect on transcutaneous oxygen pressure (TcPO2). Persons with unilateral transtibial amputation and residual limb pain of unknown origin were included. Medical history, including residual limb pain, was recorded, and the SF-36 administered. Resting TcPO2 levels were measured in the supine position and without a liner at 0, 10, 20 and 30 minutes using two sensors: one placed in the Transverse plane over the tip of the Tibia End (= TTE), the other placed in the Sagittal plane, distally over the Peroneal Compartment (= SPC). Measurements were repeated with specially prepared liners avoiding additional pressure due to sensor placement. Statistical analyses were performed using SPSS. Twenty persons (9 women, 11 men) with a mean age of 68.65 years (range 47–86 years) participated. The transtibial amputation occurred on average 43 months prior to study entry (range 3–119 months). With liner wear, both sensors measured TcPO2 levels that were significantly lower than those measured without a liner (TTE: p < 0.001; SPC: p = 0.002) after 10, 20 and 30 minutes. No significant differences were found between TcPO2 levels over time between the sensors. There were no significant associations between TcPO2 levels and pain, smoking status, age, duration of daily liner use, mobility level, and revision history. Resting TcPO2 levels decreased significantly while wearing a liner alone, without a prosthetic socket. Further studies are required to investigate the effect of liner wear on exercise TcPO2 levels.
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