High-speed intravascular photoacoustic imaging of lipid-laden atherosclerotic plaque enabled by a 2-kHz barium nitrite raman laser.
High-speed intravascular photoacoustic imaging of lipid-laden atherosclerotic plaque enabled by a 2-kHz barium nitrite raman laser.
复制标题
DOI:
10.1038/srep06889
复制
发表时间:
2014-11-04
影响因子:
4.6
通讯作者:
Cheng JX
中科院分区:
文献类型:
--
作者:
Wang P;Ma T;Slipchenko MN;Liang S;Hui J;Shung KK;Roy S;Sturek M;Zhou Q;Chen Z;Cheng JX
Lipid deposition inside the arterial wall is a key indicator of plaque vulnerability. An intravascular photoacoustic (IVPA) catheter is considered a promising device for quantifying the amount of lipid inside the arterial wall. Thus far, IVPA systems suffered from slow imaging speed (~50 s per frame) due to the lack of a suitable laser source for high-speed excitation of molecular overtone vibrations. Here, we report an improvement in IVPA imaging speed by two orders of magnitude, to 1.0 s per frame, enabled by a custom-built, 2-kHz master oscillator power amplifier (MOPA)-pumped, barium nitrite [Ba(NO3)2] Raman laser. This advancement narrows the gap in translating the IVPA technology to the clinical setting.
登录
查看更多内容
DOI:
10.1016/s0735-1097(01)01175-5
发表时间:
2001-04-01
影响因子:
24
作者:
Mintz, GS;Nissen, SE;Yock, PG
通讯作者:
Yock, PG
DOI:
10.1161/atvbaha.108.179705
发表时间:
2012-09
期刊:
Arteriosclerosis, thrombosis, and vascular biology
影响因子:
--
作者:
Libby P
通讯作者:
Libby P
影响因子:
1.5
作者:
Al-Masoodi, A. H. H.;Ismail, M. F.;Harun, Sulaiman Wadi
通讯作者:
Harun, Sulaiman Wadi
影响因子:
7.5
作者:
Thim, Troels;Hagensen, Mette Kallestrup;Falk, Erling
通讯作者:
Falk, Erling
影响因子:
5.7
作者:
Rajian, Justin Rajesh;Li, Rui;Cheng, Ji-Xin
通讯作者:
Cheng, Ji-Xin