Water-soluble amorphous iron oxide nanoparticles synthesized by a quickly pestling and nontoxic method at room temperature as MRI contrast agents
Water-soluble amorphous iron oxide nanoparticles synthesized by a quickly pestling and nontoxic method at room temperature as MRI contrast agents
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室温下快速捣碎无毒方法合成的水溶性无定形氧化铁纳米粒子作为MRI造影剂
DOI：
10.1016/j.cej.2013.09.042
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发表时间：
2014
影响因子：
15.1
通讯作者：
Jiang, Qing
中科院分区：
文献类型：
--
作者：
Yang, Ping;Lv, Zhongwen;Sun, Huan;Jiang, Qing
在无溶剂条件下，室温下合成了具有良好水溶性的无定形氧化铁纳米粒子。通过傅里叶变换红外光谱（FT-IR）、X射线衍射（XRD）、能量色散X射线光谱（EDS）、X射线光电子能谱（XPS）和透射电子显微镜（TEM）对纳米粒子进行表征，并对柠檬酸盐包覆纳米粒子的T2加权MRI图像进行了分析。该方法的优点不仅在于简单、无毒，而且成本低，非常适合于进一步的应用。这些结果表明，柠檬酸盐包被的纳米颗粒具有很大的潜力，在MRI中作为aT 2造影剂的应用。
Amorphous iron oxide (IO) nanoparticles (NPs) with excellent water-solubility were synthesized at room temperature without the presence of any solvents. The obtained nanoparticles were characterized by FT-IR (Fourier transform infrared spectroscopy), XRD (X-ray diffraction), EDS (energy dispersive X-ray spectroscopy), X-Ray photoelectron spectroscopy (XPS), and TEM (transmission electron microscopy).T2-weighted MRI images of citrate-coated NPs showed that the magnetic resonance signal is enhanced significantly with increasing nanoparticle concentration in water. Advantages of this method rely not only on the simplicity and nontoxicity but also on the low cost, highly suitable for further applications. These results indicate that the citrate-coated NPs have great potential for application in MRI as aT2contrast agent.
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影响因子：
13.3
作者：
Hacliipanayis, Coslas G.;Bonder, Michael J.;Balakrishanan, Srinivasan;Wang, Xiaoxia;Mao, Huio;Hadjipanayis, George C.
通讯作者：
Hadjipanayis, George C.
影响因子：
4.9
作者：
Pinxian Xi;Kaia Cheng;Xiaolian Sun;Z. Zeng;Shouheng Sun
通讯作者：
Pinxian Xi;Kaia Cheng;Xiaolian Sun;Z. Zeng;Shouheng Sun
由阿霉素共轭 Fe3O4 纳米颗粒核和 PEG 功能化多孔二氧化硅壳组成的新型磁性药物递送系统的合成
影响因子：
4.9
作者：
Chen, Feng-Hua;Zhang, Li-Ming;Zhang, Zhi-Jun
通讯作者：
Zhang, Zhi-Jun
影响因子：
3.5
作者：
Hsieh, S.;Huang, B. Y.;Chang, C. W.
通讯作者：
Chang, C. W.
影响因子：
4.9
作者：
Jia, Xiao;Chen, Dairong;Zhai, Shumei
通讯作者：
Zhai, Shumei