Tunable composites prepared from graphene oxide and zeolitic imidazolate framework-8 for improved selective isolation of hemoglobin

Tunable composites prepared from graphene oxide and zeolitic imidazolate framework-8 for improved selective isolation of hemoglobin
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由氧化石墨烯和咪唑骨架-8沸石制备的可调复合材料可改善血红蛋白的选择性分离

DOI:
10.1007/s00604-018-2904-5
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发表时间:
2018-07
期刊:
影响因子:
5.7
通讯作者:
Bai Qaun
Bai Qaun
中科院分区:
化学2区
文献类型:
--
作者:
Liu Jia-Wei;Liang Yi-Xun;Liang Qing-Mei;Yan Hai-Lin;Shen Ji-Wei;Wang Chao-Zhan;Bai Qaun

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作者报道了由氧化石墨烯(GO)和沸石咪唑酸骨架-8 (ZIF-GO)制备的复合材料,其中含有不同馏分的氧化石墨烯。氧化石墨烯作为模板和复合材料表面特性的调制器。它还提高了特定蛋白质的选择性吸附,即血红蛋白(Hb)在这种情况下。当氧化石墨烯含量为20%时,复合材料对Hb的吸附量高达436 mg g−1,对回收的Hb保持95%的比活性。该吸附剂用于从人全血中选择性分离Hb。摘要制备了不同氧化石墨烯质量比的氧化石墨烯-咪唑酸沸石骨架-8复合材料(ZIF-GO),以调整其表面性能并提高其对血红蛋白的吸附选择性。
The authors report on the preparation of composites made from graphene oxide (GO) and zeolitic imidazolate framework-8 (ZIF-GO), with various fractions of GO. GO acts as the template and as a modulator for the surface properties of the composites. It also improves the selective adsorption of specific proteins, i.e. hemoglobin (Hb) in this case. The adsorption capacity for Hb is as high as 436 mg g−1when using a composite containing 20% of GO as sorbent, and 95% of specific activity is maintained for the Hb recovered. The sorbent is applied to selectively isolate Hb from human whole blood.Graphical abstractGraphene oxide-zeolitic imidazolate framework-8 composites (ZIF-GO) with varying mass ratios of GO were prepared in order to tune surface properties and to improve the adsorption selectivity toward hemoglobin.
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