Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis.
Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis.
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围绝经期时，女性吸烟者的慢性阻塞性肺部疾病的风险增加了：一种系统的综述和荟萃分析。
DOI：
10.1186/1465-9921-7-52
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发表时间：
2006-03-29
影响因子：
5.8
通讯作者：
Sin, DD
中科院分区：
文献类型：
--
作者：
Gan, WQ;Man, SP;Postma, DS;Camp, P;Sin, DD
最近的报道表明，在接下来的十年中，女性慢性阻塞性肺疾病（COPD）将超过西方世界中男性的疾病，尽管在大多数司法管辖区，与男性相比，女性的吸烟率较低。雌性吸烟者在生物学上是否更容易受到COPD的影响。这项研究回顾了可用的证据，以确定与男性吸烟者相比，一秒钟（FEV1）强迫呼气量的下降速度是否更快，以及年龄是否改变了香烟烟雾与肺功能下降之间的关系。
对基于人群的队列研究进行了系统的审查和荟萃分析，该研究的随访期至少为3年，在至少两个不同的时间点上测量了FEV1，并通过性别和吸烟状况分析了FEV1数据成年人。
在646个潜在相关文章中，有11项符合这些标准，并被包括在分析中（n = 55 709名参与者）。整个研究中，与性别相关的结果存在异质性。但是，与从未和以前的吸烟者相比，目前，FEV1％预测的FEV1％的年增长率平均更高。当前女性吸烟者的年龄增长的FEV1％的年龄明显高于男性吸烟者（线性回归分析，R2 = 0.56； P = 0.008）。年龄没有实质性地影响男性和女性以前和从未吸烟的FEV1％下降率（分别为p = 0.775和p = 0.326）。
随着女性吸烟者的年龄，与雄性吸烟者相比，FEV1％的预测中似乎会加速下降。需要专门针对与性别相关的肺功能变化的未来研究来确认这些早期发现。
Recent reports indicate that over the next decade rates of chronic obstructive pulmonary disease (COPD) in women will exceed those in men in the western world, though in most jurisdictions, women continue to smoke less compared with men. Whether female adult smokers are biologically more susceptible to COPD is unknown. This study reviewed the available evidence to determine whether female adult smokers have a faster decline in forced expiratory volume in one second (FEV1) compared with male adult smokers and whether age modifies the relationship between cigarette smoke and lung function decline. A systematic review and a meta-analysis was performed of population-based cohort studies that had a follow-up period of at least 3 years, measured FEV1 on at least two different time points, and presented FEV1 data stratified by gender and smoking status in adults. Of the 646 potentially relevant articles, 11 studies met these criteria and were included in the analyses (N = 55 709 participants). There was heterogeneity in gender-related results across the studies. However, on average current smokers had a faster annual decline rate in FEV1% predicted compared with never and former smokers. Female current smokers had with increasing age a significantly faster annual decline in FEV1% predicted than male current smokers (linear regression analysis, R2 = 0.56; p = 0.008). Age did not materially affect the rate of decline in FEV1% predicted in male and female former and never smokers (p = 0.775 and p = 0.326, respectively). As female smokers age, they appear to experience an accelerated decline in FEV1% predicted compared with male smokers. Future research powered specifically on gender-related changes in lung function is needed to confirm these early findings.
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影响因子：
168.9
作者：
Chinn, S;Jarvis, D;Burney, P
通讯作者：
Burney, P
影响因子：
168.9
作者：
Hospers, JJ;Postma, DS;Schouten, JP
通讯作者：
Schouten, JP
DOI：
10.1164/rccm.200402-230oc
发表时间：
2005-01-15
影响因子：
24.7
作者：
James, AL;Palmer, LJ;Musk, AW
通讯作者：
Musk, AW
影响因子：
120.7
作者：
Michaud, CM;Murray, CJL;Bloom, BR
通讯作者：
Bloom, BR
DOI：
10.1016/0002-9378(90)90420-c
发表时间：
1990-02-01
影响因子：
9.8
作者：
BARON, JA;LAVECCHIA, C;LEVI, F
通讯作者：
LEVI, F