MUPET-Mouse Ultrasonic Profile ExTraction: A Signal Processing Tool for Rapid and Unsupervised Analysis of Ultrasonic Vocalizations.
MUPET-Mouse Ultrasonic Profile ExTraction: A Signal Processing Tool for Rapid and Unsupervised Analysis of Ultrasonic Vocalizations.
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DOI:
10.1016/j.neuron.2017.04.005
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发表时间:
2017-05-03
期刊:
影响因子:
16.2
通讯作者:
Narayanan S
中科院分区:
文献类型:
--
作者:
Van Segbroeck M;Knoll AT;Levitt P;Narayanan S
Vocalizations play a significant role in social communication across species. Analyses in rodents have used a limited number of spectro-temporal measures to compare ultrasonic vocalizations (USVs), which limits the ability to address repertoire complexity in the context of behavioral states. Using an automated and unsupervised signal processing approach, we report the development of MUPET (Mouse Ultrasonic Profile ExTraction) software, an open access MATLAB® tool that provides data-driven, high-throughput analyses of USVs. MUPET measures, learns, and compares syllable types and provides an automated time-stamp of syllable events. Using USV data from a large mouse genetic reference panel and open source datasets produced in different social contexts, MUPET analyzes the fine details of syllable production and repertoire use. MUPET thus serves as a new tool for USV repertoire analyses, with the capability to be adapted for use with other species. Van Segbroeck et al. present open-access software that uses signal-processing techniques to perform rapid, unsupervised analysis of mouse ultrasonic vocalization repertoires, including unbiased syllable discovery, new metrics to compare syllable production and use, and syllable time-stamp enabling next-step behavioral analyses.
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