THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM.
THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM.
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DOI:
10.1085/jgp.16.6.961
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发表时间:
1933-07-20
期刊:
影响因子:
--
通讯作者:
Bardwell K
中科院分区:
文献类型:
--
作者:
Baumberger JP;Jürgensen JJ;Bardwell K
1. The term "coupled redox potential" is defined. 2. The system lactic ion See PDF for Equation pyruvic ion + 2H+ + 2e is shown to be reversible (when the enzyme is lactic acid dehydrogenase) and its coupled redox potential between pH 5.2 and 7.2 at 32°C. is: See PDF for Equation 3. The free energy of the reaction: lactic ion (1m) → pyruvic ion (1m) = -ΔF = –14,572. 4. The standard free energy of formation (ΔF 298) of pyruvic acid (l) is estimated at –108,127. This is merely an approximation as some necessary data are lacking. 5. The importance of coupled redox potentials as a factor in the regulation of the equilibrium of metabolites is indicated.
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