THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM.

THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM.
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DOI:
10.1085/jgp.16.6.961
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发表时间:
1933-07-20
期刊:
The Journal of general physiology
影响因子:
--
通讯作者:
Bardwell K
Bardwell K
中科院分区:
其他
文献类型:
--
作者:
Baumberger JP;Jürgensen JJ;Bardwell K

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1.定义了术语“偶联氧化还原电位”。2.乳酸离子体系见PDF的方程式:乳酸离子+2 H + +2 e被证明是可逆的(当酶是乳酸脱氢酶时),其偶联氧化还原电位在32°C时在pH 5.2和7.2之间。参见PDF中的公式3。反应的自由能:乳酸离子(1 m)→乳酸离子(1 m)= -ΔF =-14,572。4.标准生成自由能(ΔF 298)估计为-108,127。这只是一个近似值,因为缺乏一些必要的数据。5.耦合氧化还原电位的重要性,作为一个因素,在调节代谢物的平衡。
1. The term "coupled redox potential" is defined. 2. The system lactic ion See PDF for Equation pyruvic ion + 2H+ + 2e is shown to be reversible (when the enzyme is lactic acid dehydrogenase) and its coupled redox potential between pH 5.2 and 7.2 at 32°C. is: See PDF for Equation 3. The free energy of the reaction: lactic ion (1m) → pyruvic ion (1m) = -ΔF = –14,572. 4. The standard free energy of formation (ΔF 298) of pyruvic acid (l) is estimated at –108,127. This is merely an approximation as some necessary data are lacking. 5. The importance of coupled redox potentials as a factor in the regulation of the equilibrium of metabolites is indicated.
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发表时间: 1927-01-01
影响因子: 4.1
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