The potential economic value of a Staphylococcus aureus vaccine for neonates.
The potential economic value of a Staphylococcus aureus vaccine for neonates.
复制标题
新生儿金黄色葡萄球菌疫苗的潜在经济价值。
DOI:
10.1016/j.vaccine.2010.04.069
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发表时间:
2010
期刊:
影响因子:
5.5
通讯作者:
Muder,RobertR
中科院分区:
文献类型:
--
作者:
Lee,BruceY;Ufberg,PaulJ;Bailey,RachelR;Wiringa,AnnE;Smith,KennethJ;Nowalk,AndrewJ;Higgins,Conor;Wateska,AngelaR;Muder,RobertR
The continuing morbidity and mortality associated with Staphylococcus aureus (S. aureus) infections, especially methicillin-resistant S. aureus (MRSA) infections, have motivated calls to make S. aureus vaccine development a research priority. We developed a decision analytic computer simulation model to determine the potential economic impact of a S. aureus vaccine for neonates. Our results suggest that a S. aureus vaccine for the neonatal population would be strongly cost-effective (and in many situations dominant) over a wide range of vaccine efficacies (down to 10%) for vaccine costs (≤$500), and S. aureus attack rates (≥1%).
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