High spatial resolution imaging mass spectrometry and classical histology on a single tissue section.

High spatial resolution imaging mass spectrometry and classical histology on a single tissue section.
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DOI:
10.1002/jms.1926
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发表时间:
2011-06
影响因子:
2.3
通讯作者:
Caprioli, Richard M.
Caprioli, Richard M.
中科院分区:
化学4区
文献类型:
--
作者:
Deutskens, Fabian;Yang, Junhai;Caprioli, Richard M.

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本报告中介绍的工作描述并演示了使用MALDI IMS对生物组织进行蛋白质成像分析的方案,其中组织学染色和质谱分析在同一组织切片上进行。大鼠小脑矢状面切片的空间图像分辨率为35 μm。
The work presented in this report describes and demonstrates a protocol for protein imaging analysis of biological tissue using MALDI IMS where histological staining and MS analysis are performed on the same tissue section. Spatial image resolution is shown at 35 μm for saggital sections of the cerebellum from rat brain.
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