Relevance of the glutathione system in temporal lobe epilepsy: evidence in human and experimental models.
Relevance of the glutathione system in temporal lobe epilepsy: evidence in human and experimental models.
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DOI：
10.1155/2014/759293
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发表时间：
2014
影响因子：
--
通讯作者：
Carmona-Aparicio L
中科院分区：
文献类型：
--
作者：
Cárdenas-Rodríguez N;Coballase-Urrutia E;Pérez-Cruz C;Montesinos-Correa H;Rivera-Espinosa L;Sampieri A 3rd;Carmona-Aparicio L
氧化应激是由多种因素引起的活性氧和氮产生失衡的状态。这种生化状态与全身性疾病以及影响中枢神经系统的疾病有关。癫痫是一种慢性神经系统疾病，估计颞叶癫痫占所有癫痫病例的40%。目前，来自人类和实验模型的证据支持癫痫发作和癫痫发生过程中氧化应激的参与。因此，本综述的目的是提供有助于处理这些证据的信息，并调查这种特定病理学的生化状态的治疗影响。
Oxidative stress, which is a state of imbalance in the production of reactive oxygen species and nitrogen, is induced by a wide variety of factors. This biochemical state is associated with diseases that are systemic as well as diseases that affect the central nervous system. Epilepsy is a chronic neurological disorder, and temporal lobe epilepsy represents an estimated 40% of all epilepsy cases. Currently, evidence from human and experimental models supports the involvement of oxidative stress during seizures and in the epileptogenesis process. Hence, the aim of this review was to provide information that facilitates the processing of this evidence and investigate the therapeutic impact of the biochemical status for this specific pathology.
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影响因子：
9
作者：
通讯作者：
--
影响因子：
2.5
作者：
Choo, YS;Mao, ZK;Lesort, M
通讯作者：
Lesort, M
影响因子：
3.8
作者：
Ashrafi, Mahmood Reza;Shabanian, Reza;Pourpak, Zahra
通讯作者：
Pourpak, Zahra
DOI：
10.1007/bf03159937
发表时间：
1991-06-01
期刊：
MOLECULAR AND CHEMICAL NEUROPATHOLOGY
影响因子：
--
作者：
ADAMS, JD;KLAIDMAN, LK;MILLER, CA
通讯作者：
MILLER, CA
影响因子：
11.2
作者：
Bough, Kristopher J.;Wetherington, Jonathon;Dingledine, Raymond J.
通讯作者：
Dingledine, Raymond J.