The social construction of genomics and genetic analysis in ocular diseases in Ibadan, South-western Nigeria.
The social construction of genomics and genetic analysis in ocular diseases in Ibadan, South-western Nigeria.
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DOI：
10.1371/journal.pone.0278286
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
基因组学是一个新兴的领域，以改善公共卫生实践，有潜在的好处，了解眼部疾病。本研究通过两次焦点小组讨论和12次在眼疾患者中进行的深入访谈，探讨了尼日利亚伊巴丹盲人社区眼疾基因组学的社会构建。这些数据是按主题和内容分析的。虽然参与者对眼部疾病，基因组学及其关系的知识有限，但他们对它的潜在益处保持积极的态度。这使他们愿意参与眼科疾病的基因组学检测。参与者更喜欢基于唾液的样本收集，而不是基于血液的样本收集，并对基因组学研究的程序和累积利益表示担忧。因此，公众对眼部疾病和以客户为中心的基因组学测试程序的敏感性应该产生。
Genomics, an emerging field to improve public health practice, has potential benefits to understanding ocular diseases. This study explored the social construction of genomics in ocular diseases in the blind community in Ibadan, Nigeria, through two focus group discussions and twelve in-depth interview sessions conducted among people living with ocular disorders. The data were thematic and content-analysed. Although the participants had limited knowledge about ocular diseases, genomics, and their nexus, they maintained a positive attitude toward its potential benefits. This informed their willingness to participate in genomics testing for ocular diseases. The participants preferred saliva-based sample collection over blood-based, and expressed concern for the procedure and accrued benefits of genomics studies. Thus, public sensitisation about ocular diseases and client-centred genomics testing procedures should be engendered.
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