Molecular mechanisms of astrocyte-induced synaptogenesis.
Molecular mechanisms of astrocyte-induced synaptogenesis.
复制标题
星形胶质细胞诱导的突触发生的分子机制。
DOI：
10.1016/j.conb.2017.05.006
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发表时间：
2017-08
影响因子：
5.7
通讯作者：
Eroglu C
中科院分区：
文献类型：
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作者：
Baldwin KT;Eroglu C
星形胶质细胞是形态复杂的细胞，在大脑中执行各种各样的关键功能。作为突触的结构和功能整合的组分，星形胶质细胞分泌蛋白质、脂质和小分子，其结合神经元受体以促进突触发生并调节突触连接。此外，星形胶质细胞是回路形成的关键参与者，指导不同类别神经元之间的突触形成。本文综述了最近发表的关于星形胶质细胞介导的突触发生的文章，重点是星形胶质细胞协调突触回路形成的分子机制。
Astrocytes are morphologically complex cells that perform a wide variety of critical functions in the brain. As a structurally and functionally integrated component of the synapse, astrocytes secrete proteins, lipids, and small molecules that bind neuronal receptors to promote synaptogenesis and regulate synaptic connectivity. Additionally, astrocytes are key players in circuit formation, instructing the formation of synapses between distinct classes of neurons. This review highlights recent publications on the topic of astrocyte-mediated synaptogenesis, with a focus on the molecular mechanisms through which astrocytes orchestrate the formation of synaptic circuits.
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影响因子：
64.8
作者：
Iossifov, Ivan;O'Roak, Brian J.;Sanders, Stephan J.;Ronemus, Michael;Krumm, Niklas;Levy, Dan;Stessman, Holly A.;Witherspoon, Kali T.;Vives, Laura;Patterson, Karynne E.;Smith, Joshua D.;Paeper, Bryan;Nickerson, Deborah A.;Dea, Jeanselle;Dong, Shan;Gonzalez, Luis E.;Mandell, Jeffrey D.;Mane, Shrikant M.;Murtha, Michael T.;Sullivan, Catherine A.;Walker, Michael F.;Waqar, Zainulabedin;Wei, Liping;Willsey, A. Jeremy;Yamrom, Boris;Lee, Yoon-ha;Grabowska, Ewa;Dalkic, Ertugrul;Wang, Zihua;Marks, Steven;Andrews, Peter;Leotta, Anthony;Kendall, Jude;Hakker, Inessa;Rosenbaum, Julie;Ma, Beicong;Rodgers, Linda;Troge, Jennifer;Narzisi, Giuseppe;Yoon, Seungtai;Schatz, Michael C.;Ye, Kenny;McCombie, W. Richard;Shendure, Jay;Eichler, Evan E.;State, Matthew W.;Wigler, Michael
通讯作者：
Wigler, Michael
DOI：
10.1007/978-3-7091-0932-8_5
发表时间：
2012-01-01
期刊：
SYNAPTIC PLASTICITY: DYNAMICS, DEVELOPMENT AND DISEASE
影响因子：
--
作者：
Bukalo, Olena;Dityatev, Alexander
通讯作者：
Dityatev, Alexander
影响因子：
9.2
作者：
Bernardinelli, Yann;Randall, Jerome;Muller, Dominique
通讯作者：
Muller, Dominique
影响因子：
23.9
作者：
Han, Xiaoning;Chen, Michael;Wang, Fushun;Windrem, Martha;Wang, Su;Shanz, Steven;Xu, Qiwu;Oberheim, Nancy Ann;Bekar, Lane;Betstadt, Sarah;Silva, Alcino J.;Takano, Takahiro;Goldman, Steven A.;Nedergaard, Maiken
通讯作者：
Nedergaard, Maiken
影响因子：
64.8
作者：
通讯作者：
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