Utilization of a 3D printer to fabricate boluses used for electron therapy of skin lesions of the eye canthi.
Utilization of a 3D printer to fabricate boluses used for electron therapy of skin lesions of the eye canthi.
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DOI：
10.1002/acm2.12013
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发表时间：
2017-01
影响因子：
2.1
通讯作者：
Falco M
中科院分区：
文献类型：
--
作者：
Łukowiak M;Jezierska K;Boehlke M;Więcko M;Łukowiak A;Podraza W;Lewocki M;Masojć B;Falco M
这项工作描述了使用3D打印技术为接受电子束治疗的患者创建个性化的推注，用于治疗眼部皮肤病变。它旨在证明3D打印的有效性超过手动制造的石蜡团。该研究涉及11名患者，他们需要构建单独的推注。采集制造的3D打印推注和石蜡推注的CT扫描，并叠加到患者CT扫描上，以比较其拟合、推注均匀性和基础剂量分布。为了量化匹配水平，使用了多个度量。匹配水平指数（ML）值范围为0 - 100%，其中100%表示参考团注（在治疗计划系统中计划）与3D打印和石蜡团注之间的完美匹配。3D打印推注的平均ML（± 1 SD）为95.1 ± 2.1%，而手动制造的石蜡推注为46.0 ± 10.1%。相应地，与手动制造的石蜡推注相比，3D打印推注的剂量分布的平均剂量更接近处方剂量，并且剂量扩散更小。得出的结论是，3D打印技术是制造用于小眼部病变的团注的可行方法，并且提供的团注上级于我们用石蜡片手动制造的团注。
This work describes the use of 3D printing technology to create individualized boluses for patients treated with electron beam therapy for skin lesions of the eye canthi. It aimed to demonstrate the effectiveness of 3D‐printed over manually fabricated paraffin boluses. The study involved 11 patients for whom the construction of individual boluses were required. CT scans of the fabricated 3D‐printed boluses and paraffin boluses were acquired and superimposed onto patient CT scans to compare their fitting, bolus homogeneity, and underlying dose distribution. To quantify the level of matching, multiple metrics were utilized. Matching Level Index (ML) values ranged from 0 to 100%, where 100% indicated a perfect fit between the reference bolus (planned in treatment planning system) and 3D‐printed and paraffin bolus. The average ML (± 1 SD) of the 3D‐printed boluses was 95.1 ± 2.1%, compared to 46.0 ± 10.1% for the manually fabricated paraffin bolus. Correspondingly, mean doses were closer to the prescribed doses, and dose spreads were less for the dose distributions from the 3D‐printed boluses, as compared to those for the manually fabricated paraffin boluses. It was concluded that 3D‐printing technology is a viable method for fabricating boluses for small eye lesions and provides boluses superior to our boluses manually fabricated from paraffin sheets.
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影响因子：
2
作者：
Inaba K;Ito Y;Suzuki S;Sekii S;Takahashi K;Kuroda Y;Murakami N;Morota M;Mayahara H;Sumi M;Uno T;Itami J
通讯作者：
Itami J
影响因子：
2.1
作者：
Su S;Moran K;Robar JL
通讯作者：
Robar JL
影响因子：
3
作者：
ABRAHAM, JC;JABALEY, ME;HOOPES, JE
通讯作者：
HOOPES, JE
影响因子：
5.7
作者：
Maingon, P;Truc, G;Horiot, JC
通讯作者：
Horiot, JC
影响因子：
3.8
作者：
Kawrakow, I;Fippel, M;Friedrich, K
通讯作者：
Friedrich, K