Sl-IAA3, a tomato Aux/IAA at the crossroads of auxin and ethylene signalling involved in differential growth.
Sl-IAA3, a tomato Aux/IAA at the crossroads of auxin and ethylene signalling involved in differential growth.
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DOI：
10.1093/jxb/erp009
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发表时间：
2009
影响因子：
6.9
通讯作者：
Bouzayen M
中科院分区：
文献类型：
--
作者：
Chaabouni S;Jones B;Delalande C;Wang H;Li Z;Mila I;Frasse P;Latché A;Pech JC;Bouzayen M
尽管多种激素的相互作用对于大多数植物发育过程是必不可少的，但关键的整合分子参与者仍然在很大程度上未被发现或未被表征。番茄生长素/吲哚-3-乙酸（Aux/IAA）基因家族的成员S1-IAA 3与生长素和乙烯信号转导途径交叉。Aux/IAA基因编码短寿命的转录调节子，对生长素反应的控制起着重要作用。它们的功能主要由拟南芥中的显性、功能获得性突变等位基因来定义。S1-IAA 3基因编码可抑制来自生长素应答启动子的转录的核靶向蛋白。S1-IAA 3表达是生长素和乙烯依赖性的，在紧密的组织特异性基础上被调节，并且与经历差异生长的组织例如在上位叶柄和顶钩中相关。S1-IAA 3的反义下调导致生长素和乙烯相关的表型，包括改变的顶端优势、较低的生长素敏感性、在黑暗中夸大的顶端钩曲率和在光照下减少的叶柄上向性。这些结果为Aux/IAAs的作用提供了新的见解，并将S1-IAA 3蛋白定位在番茄中生长素和乙烯信号传导的十字路口。
Whereas the interplay of multiple hormones is essential for most plant developmental processes, the key integrating molecular players remain largely undiscovered or uncharacterized. It is shown here that a member of the tomato auxin/indole-3-acetic acid (Aux/IAA) gene family, Sl-IAA3, intersects the auxin and ethylene signal transduction pathways. Aux/IAA genes encode short-lived transcriptional regulators central to the control of auxin responses. Their functions have been defined primarily by dominant, gain-of-function mutant alleles in Arabidopsis. The Sl-IAA3 gene encodes a nuclear-targeted protein that can repress transcription from auxin-responsive promoters. Sl-IAA3 expression is auxin and ethylene dependent, is regulated on a tight tissue-specific basis, and is associated with tissues undergoing differential growth such as in epinastic petioles and apical hook. Antisense down-regulation of Sl-IAA3 results in auxin and ethylene-related phenotypes, including altered apical dominance, lower auxin sensitivity, exaggerated apical hook curvature in the dark and reduced petiole epinasty in the light. The results provide novel insights into the roles of Aux/IAAs and position the Sl-IAA3 protein at the crossroads of auxin and ethylene signalling in tomato.
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影响因子：
6.5
作者：
Kloosterman, B.;Visser, R. G. F.;Bachem, C. W. B.
通讯作者：
Bachem, C. W. B.
影响因子：
56.9
作者：
BLEECKER, AB;ESTELLE, MA;KENDE, H
通讯作者：
KENDE, H
影响因子：
5.1
作者：
Liscum, E;Reed, JW
通讯作者：
Reed, JW
影响因子：
11.6
作者：
LINCOLN, C;BRITTON, JH;ESTELLE, M
通讯作者：
ESTELLE, M
影响因子：
64.8
作者：
Kepinski, S;Leyser, O
通讯作者：
Leyser, O