Pathophysiology and Treatment of Memory Dysfunction After Traumatic Brain Injury.
Pathophysiology and Treatment of Memory Dysfunction After Traumatic Brain Injury.
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DOI：
10.1007/s11910-017-0762-x
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发表时间：
2017-07
影响因子：
5.6
通讯作者：
Cohen AS
中科院分区：
文献类型：
--
作者：
Paterno R;Folweiler KA;Cohen AS
Memory is fundamental to everyday life, and cognitive impairments resulting from traumatic brain injury (TBI) have devastating effects on TBI survivors. A contributing component to memory impairments caused by TBI are alterations in the neural circuits associated with memory function. In this review, we aim to bring together experimental findings that characterize behavioral memory deficits and the underlying pathophysiology of memory-involved circuits after TBI. While there is little doubt that TBI causes memory and cognitive dysfunction, it is difficult to conclude which memory phase i.e., encoding, maintenance or retrieval is specifically altered by TBI. This is most likely due to variation in behavioral protocols and experimental models. Additionally we review a selection of experimental treatments that hold translational potential to mitigate memory dysfunction following injury.
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影响因子：
1.9
作者：
Darwish H;Mahmood A;Schallert T;Chopp M;Therrien B
通讯作者：
Therrien B
DOI：
10.1037/h0077579
发表时间：
1979-01-01
期刊：
JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
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5.3
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Braga, Maria F. M.