Dementia: timely diagnosis and early intervention.
Dementia: timely diagnosis and early intervention.
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DOI：
10.1136/bmj.h3029
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发表时间：
2015-06-16
期刊：
影响因子：
--
通讯作者：
Taylor JP
中科院分区：
文献类型：
--
作者：
Robinson L;Tang E;Taylor JP
痴呆症是一种临床综合症，包括记忆、语言和行为方面的困难，导致日常生活活动受损。阿尔茨海默病是最常见的痴呆亚型，其次是血管性痴呆、混合性痴呆和路易体痴呆。由于全球人口正在迅速老龄化，痴呆症已成为全球关注的问题1；这种疾病给个人及其家庭以及提供保健和社会护理带来了相当大的负担。到2050年，估计全世界将有1.35亿人患有痴呆症。2010年，全球痴呆症护理费用估计为6040亿美元（3960亿英镑；5480亿欧元），预计到2030年将增加到1万亿美元。1在所有慢性疾病中，痴呆症是导致依赖和残疾的最重要因素之一。在无法治愈的情况下，一种认为无能为力的专业信念导致了诊断的延误。然而，越来越多的证据表明痴呆症是可以预防的，这使得国际社会开始关注早期诊断和干预。本综述旨在总结当前痴呆诊断和早期干预的证据和最佳实践。
Dementia describes a clinical syndrome that encompasses difficulties in memory, language, and behaviour that leads to impairments in activities of daily living. Alzheimer’s disease is the most common subtype of dementia, followed by vascular dementia, mixed dementia, and dementia with Lewy bodies. Because the global population is rapidly ageing, dementia has become a concern worldwide1; the illness places considerable burden on individuals and their families and also on health and social care provision.By 2050 an estimated 135 million people worldwide will have dementia. In 2010 the global cost of dementia care was estimated at $604 bn (£ 396bn;€ 548bn) and estimated to increase to $1 tr by 2030. 1 Of all chronic diseases, dementia is one of the most important contributors to dependence and disability. 2 3 In the absence of a cure, a professional belief that nothing can be done has contributed to delays in diagnosis. 4 However, increasing evidence showing that dementia may be preventable1 5 has led to an international focus on earlier diagnosis and intervention. 6 This review aims to summarise current evidence and best practice in the diagnosis and early intervention in dementia care.
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影响因子：
168.9
作者：
Matthews, Fiona E.;Arthur, Antony;Barnes, Linda E.;Bond, John;Jagger, Carol;Robinson, Louise;Brayne, Carol
通讯作者：
Brayne, Carol
DOI：
10.1016/j.jalz.2011.03.005
发表时间：
2011-05
期刊：
Alzheimer's & dementia : the journal of the Alzheimer's Association
影响因子：
--
作者：
McKhann GM;Knopman DS;Chertkow H;Hyman BT;Jack CR Jr;Kawas CH;Klunk WE;Koroshetz WJ;Manly JJ;Mayeux R;Mohs RC;Morris JC;Rossor MN;Scheltens P;Carrillo MC;Thies B;Weintraub S;Phelps CH
通讯作者：
Phelps CH
影响因子：
4
作者：
Mioshi, Eneida;Dawson, Kate;Hodges, John R.
通讯作者：
Hodges, John R.
影响因子：
2.2
作者：
Bamford, Claire;Eccles, Martin;Robinson, Louise
通讯作者：
Robinson, Louise
DOI：
10.1016/j.jalz.2011.03.004
发表时间：
2011-05
期刊：
Alzheimer's & dementia : the journal of the Alzheimer's Association
影响因子：
--
作者：
Jack CR Jr;Albert MS;Knopman DS;McKhann GM;Sperling RA;Carrillo MC;Thies B;Phelps CH
通讯作者：
Phelps CH