Increase of ATP level in human erythrocytes induced by S-adenosyl-L-methionine.

Increase of ATP level in human erythrocytes induced by S-adenosyl-L-methionine.
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S-腺苷-L-甲硫氨酸诱导人红细胞中 ATP 水平增加。

DOI:
10.1016/0006-2952(86)90358-8
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发表时间:
1986
影响因子:
5.8
通讯作者:
T. Shiga
T. Shiga
中科院分区:
医学2区
文献类型:
--
作者:
N. Maeda;K. Kon;M. Sekiya;T. Shiga

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研究了s -腺苷-l-蛋氨酸(SAM)对人红细胞ATP水平、形态和变形能力的影响,并与腺苷进行了比较。(i)与SAM孵育后,新鲜细胞(年轻细胞和老年细胞的ATP水平均有相似程度的增加)和储存细胞(部分ATP耗尽)的ATP水平显著增加。(2)储存细胞经SAM处理后,IMP水平几乎不受影响(甚至降低),而经腺苷处理后,IMP(和ITP)水平显著升高。(iii)与腺苷处理相比,SAM处理后红细胞的形态和变形能力得到了很好的保存。SAM对老年细胞有一定的诱导作用,而对年轻细胞无诱导作用。
The effect of S-adenosyl-l-methionine (SAM) on the ATP level, the morphology and the deformability of human erythrocytes was investigated and compared with that of adenosine.(i) Upon incubation with SAM, the ATP level increased considerably in fresh cells (in both young and old cells in similar extent) and in stored (partially ATP-depleted) cells. But the incubation with adenosine increased ATP level to a lesser extent,(ii) The incubation of stored cells with SAM hardly affected (or rather decreased) the IMP level, while that with adenosine remarkably increased IMP (and ITP).(iii) The morphology and the deformability of stored erythrocytes were well conserved in spite of the treatment with SAM, as compared with the treatment with adenosine. The echinocytic transformation was induced in old cells to some extent by SAM, while did not in young cells.
完整人红细胞中细胞骨架和膜蛋白的可逆甲基化。
DOI: --
发表时间: 1981
期刊: The Journal of biological chemistry
影响因子: --
作者:
Freitag,C;Clarke,S
通讯作者: Clarke,S
DOI: --
发表时间: 1983
期刊: The Journal of biological chemistry
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外源甲基供体对完整人红细胞的差异膜蛋白羧甲基化。
DOI: 10.1042/bj2190743
发表时间: 1984
期刊: The Biochemical journal
影响因子: --
作者:
Ro,JY;DiMaria,P;Kim,S
通讯作者: Kim,S
DOI: 10.1016/0006-291x(84)90390-5
发表时间: 1984
影响因子: 3.1
作者:
Barber,JR;Clarke,S
通讯作者: Clarke,S
DOI: --
发表时间: 1984
期刊: The Journal of biological chemistry
影响因子: --
作者:
O'Connor,CM;Clarke,S
通讯作者: Clarke,S