European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies.
European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies.
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DOI：
10.1136/ard.2009.117200
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发表时间：
2010-07
影响因子：
27.4
通讯作者：
Carmona L
中科院分区：
文献类型：
--
作者：
Mosca M;Tani C;Aringer M;Bombardieri S;Boumpas D;Brey R;Cervera R;Doria A;Jayne D;Khamashta MA;Kuhn A;Gordon C;Petri M;Rekvig OP;Schneider M;Sherer Y;Shoenfeld Y;Smolen JS;Talarico R;Tincani A;van Vollenhoven RF;Ward MM;Werth VP;Carmona L
为在临床实践和观察性研究中监测系统性红斑狼疮（SLE）患者制定建议，并制定标准化的核心变量集以监测SLE。我们遵循欧洲反风湿联盟（EULAR）的标准化程序制定指南。采用以下技术：名义团体，德尔菲调查的优先顺序，小组讨论，系统的文献综述和两个德尔菲轮，以获得协议。小组成员包括风湿病学家、内科医生、皮肤科医生、一名肾病学家和一名与国家研究机构有关的专家。根据牛津循证医学中心的证据等级和推荐等级确定证据等级和推荐等级。共制定了10项建议，涵盖以下方面：患者评估、心血管风险因素、其他风险因素（骨质疏松症、癌症）、感染风险（筛查、疫苗接种、监测）、评估频率、实验室检查、皮肤粘膜受累、肾脏监测、神经心理学表现和眼科评估。一个“核心集”的最小变量的评估和监测SLE患者在临床实践中开发，其中包括一些建议。除建议外，还讨论了被视为药物临床试验质量管理规范一部分的特定器官评估适应症，并将其纳入流程图中。在常规临床实践中，已经制定了一套监测SLE患者的建议。使用标准化核心集监测SLE患者应有助于临床实践，以及SLE患者护理的质量控制，以及观察性研究中数据的收集和比较。
To develop recommendations for monitoring patients with systemic lupus erythematosus (SLE) in clinical practice and observational studies and to develop a standardised core set of variables to monitor SLE. We followed the European League Against Rheumatism (EULAR) standardised procedures for guideline development. The following techniques were applied: nominal groups, Delphi surveys for prioritisation, small group discussion, systematic literature review and two Delphi rounds to obtain agreement. The panel included rheumatologists, internists, dermatologists, a nephrologist and an expert related to national research agencies. The level of evidence and grading of recommendations were determined according to the Levels of Evidence and Grades of Recommendations of the Oxford Centre for Evidence-Based Medicine. A total of 10 recommendations have been developed, covering the following aspects: patient assessment, cardiovascular risk factors, other risk factors (osteoporosis, cancer), infection risk (screening, vaccination, monitoring), frequency of assessments, laboratory tests, mucocutaneous involvement, kidney monitoring, neuropsychological manifestations and ophthalmology assessment. A ‘core set’ of minimal variables for the assessment and monitoring of patients with SLE in clinical practice was developed that included some of the recommendations. In addition to the recommendations, indications for specific organ assessments that were viewed as part of good clinical practice were discussed and included in the flow chart. A set of recommendations for monitoring patients with SLE in routine clinical practice has been developed. The use of a standardised core set to monitor patients with SLE should facilitate clinical practice, as well as the quality control of care for patients with SLE, and the collection and comparison of data in observational studies.
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狼疮护理和结果的差异。
影响因子：
5.1
作者：
Demas KL;Costenbader KH
通讯作者：
Costenbader KH
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Steiner, G
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Erdozain, JG;Ruiz-Irastorza, G;Aguirre, C
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