Diabetes mellitus in centenarians.
Diabetes mellitus in centenarians.
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DOI：
10.1111/j.1532-5415.2011.03836.x
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发表时间：
2012-03
影响因子：
6.3
通讯作者：
Georgia Centenarian Study
中科院分区：
文献类型：
--
作者：
Davey A;Lele U;Elias MF;Dore GA;Siegler IC;Johnson MA;Hausman DB;Tenover JL;Poon LW;Georgia Centenarian Study
Describe prevalence of diabetes mellitus among centenarians.跨部门的、基于人口的。乔治亚州北部 44 个县。 244 centenarians (aged 98-108, 15.8% men, 20.5% African-American, 38.0% community-dwelling) from the Georgia Centenarian Study (2001-2009). Nonfasting blood samples assessed HbA1c and relevant clinical parameters. Demographic, diagnosis, and diabetes complications covariates were assessed. 12.5% of centenarians were known to have diabetes.糖尿病在非裔美国人 (27.7%) 中的患病率高于白人 (8.6%, p=.0002)。男性（16.7%）和女性（11.7%，p=.414）、居住在社区（10.2%）或设施中的百岁老人（13.9%，p=.540）之间没有差异。 Diabetes was more prevalent among overweight/obese (23.1%) than non-overweight (7.1%, p=.002) centenarians.患有糖尿病的百岁老人比没有糖尿病的百岁老人更常见贫血（78.6% 比 48.3%，p=.004）和高血压（79.3% 比 58.6%，p=.041），并且患有糖尿病的百岁老人服用更多的非降血糖药物（8.6 比 7.0，p=.023）。血红蛋白 A1c < 6.5% 的百岁老人的随机血糖水平没有超过 200 mg/dl。 Diabetes was not associated with 12 month all-cause mortality, visual impairment, amputations, cardiovascular disease or neuropathy. 37% of centenarians reported onset before age 80 (survivors), 47% between 80 and 97 years (delayers) and 15% age 98 or older (escapers). Diabetes is a risk factor for cardiovascular disease and mortality, but is seen in persons who live into very old age. Aside from higher rates of anemia and use of more medications, few clinical correlates of diabetes were observed in centenarians.
Describe prevalence of diabetes mellitus among centenarians. Cross-sectional, population-based. 44 counties in northern Georgia. 244 centenarians (aged 98-108, 15.8% men, 20.5% African-American, 38.0% community-dwelling) from the Georgia Centenarian Study (2001-2009). Nonfasting blood samples assessed HbA1c and relevant clinical parameters. Demographic, diagnosis, and diabetes complications covariates were assessed. 12.5% of centenarians were known to have diabetes. Diabetes was more prevalent among African-Americans (27.7%) than Whites (8.6%, p=.0002). There were no differences between men (16.7%) and women (11.7%, p=.414), centenarians living in the community (10.2%) or facilities (13.9%, p=.540). Diabetes was more prevalent among overweight/obese (23.1%) than non-overweight (7.1%, p=.002) centenarians. Anemia (78.6% versus 48.3%, p=.004) and hypertension (79.3% versus 58.6%, p=.041) were more prevalent among centenarians with diabetes than without and centenarians with diabetes took more nonhypoglycemic medications(8.6 versus 7.0, p=.023). No centenarians with hemoglobin A1c < 6.5% had random serum glucose levels above 200 mg/dl. Diabetes was not associated with 12 month all-cause mortality, visual impairment, amputations, cardiovascular disease or neuropathy. 37% of centenarians reported onset before age 80 (survivors), 47% between 80 and 97 years (delayers) and 15% age 98 or older (escapers). Diabetes is a risk factor for cardiovascular disease and mortality, but is seen in persons who live into very old age. Aside from higher rates of anemia and use of more medications, few clinical correlates of diabetes were observed in centenarians.
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影响因子：
16.2
作者：
Christensen DL;Witte DR;Kaduka L;Jørgensen ME;Borch-Johnsen K;Mohan V;Shaw JE;Tabák AG;Vistisen D
通讯作者：
Vistisen D
糖尿病的医疗标准 - 2010年。
影响因子：
16.2
作者：
American Diabetes Association
通讯作者：
American Diabetes Association
影响因子：
168.9
作者：
Christensen, Kaare;Doblhammer, Gabriele;Rau, Roland;Vaupel, James W.
通讯作者：
Vaupel, James W.
影响因子：
16.2
作者：
Cowie CC;Rust KF;Ford ES;Eberhardt MS;Byrd-Holt DD;Li C;Williams DE;Gregg EW;Bainbridge KE;Saydah SH;Geiss LS
通讯作者：
Geiss LS
影响因子：
16.2
作者：
Gregg, EW;Breckles, GLA;Narayan, KMV
通讯作者：
Narayan, KMV