Mouse vocal communication system: are ultrasounds learned or innate?
Mouse vocal communication system: are ultrasounds learned or innate?
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DOI：
10.1016/j.bandl.2012.10.002
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发表时间：
2013-01
影响因子：
2.5
通讯作者：
Jarvis, Erich D.
中科院分区：
文献类型：
--
作者：
Arriaga, Gustavo;Jarvis, Erich D.
关键词：
小鼠超声发声（USV）通常用作内部状态的行为读数，以测量社会和药理学操作的影响，以及用于神经精神和神经退行性疾病的小鼠模型的行为表型。然而，很少有人知道啮齿动物USV生产的神经生物学机制。在这里，我们讨论了现有的数据，以评估是否雄性小鼠的歌曲行为和支持的大脑回路类似于那些已知的声乐非学习或声乐学习物种。最近的神经生物学研究表明，小鼠USV脑系统包括运动皮层和纹状体区域，并且发声运动皮层向脑干发声运动核团发出直接的稀疏投射，这种投射被认为是哺乳动物中人类所特有的。最近的行为研究报告了相反的结论小鼠的声音可塑性，包括声音个体发育的变化USVs在早期发展，可能无法解释的先天成熟过程中，证据和反对的听觉反馈在发展和维持正常的小鼠USVs的作用，和证据和反对有限的声乐模仿的歌曲音高。为了调和这些发现，我们认为，语音学习的特点可能不是二分法，但包括一系列广泛的行为和神经特征，我们称之为连续统假设，小鼠具有一些与有限的语音学习能力相关的特征。
Mouse ultrasonic vocalizations (USVs) are often used as behavioral readouts of internal states, to measure effects of social and pharmacological manipulations, and for behavioral phenotyping of mouse models for neuropsychiatric and neurodegenerative disorders. However, little is known about the neurobiological mechanisms of rodent USV production. Here we discuss the available data to assess whether male mouse song behavior and the supporting brain circuits resemble those of known vocal non-learning or vocal learning species. Recent neurobiology studies have demonstrated that the mouse USV brain system includes motor cortex and striatal regions, and that the vocal motor cortex sends a direct sparse projection to the brainstem vocal motor nucleus ambiguous, a projection thought be unique to humans among mammals. Recent behavioral studies have reported opposing conclusions on mouse vocal plasticity, including vocal ontogeny changes in USVs over early development that might not be explained by innate maturation processes, evidence for and against a role for auditory feedback in developing and maintaining normal mouse USVs, and evidence for and against limited vocal imitation of song pitch. To reconcile these findings, we suggest that the trait of vocal learning may not be dichotomous but encompass a broad set of behavioral and neural traits we call the continuum hypothesis, and that mice possess some of the traits associated with a capacity for limited vocal learning.
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DOI：
10.1098/rspb.1998.0286
发表时间：
1998-02-07
影响因子：
4.7
作者：
Boughman, JW
通讯作者：
Boughman, JW
影响因子：
3.7
作者：
Coudé G;Ferrari PF;Rodà F;Maranesi M;Borelli E;Veroni V;Monti F;Rozzi S;Fogassi L
通讯作者：
Fogassi L
影响因子：
2.5
作者：
BOTTJER, SW;HALSEMA, KA;MIESNER, EA
通讯作者：
MIESNER, EA
影响因子：
3.3
作者：
Ennis, M;Xu, SJ;Rizvi, TA
通讯作者：
Rizvi, TA
影响因子：
3.7
作者：
Chabout J;Serreau P;Ey E;Bellier L;Aubin T;Bourgeron T;Granon S
通讯作者：
Granon S