Heterosexually acquired HTLV-III/LAV disease (AIDS-related complex and AIDS). Epidemiologic evidence for female-to-male transmission.

Heterosexually acquired HTLV-III/LAV disease (AIDS-related complex and AIDS). Epidemiologic evidence for female-to-male transmission.
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异性获得 HTLV-III/LAV 疾病(艾滋病相关综合症和艾滋病)。

DOI:
10.1001/jama.1985.03360150070026
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发表时间:
1985
期刊:
JAMA
影响因子:
--
通讯作者:
R. Gallo
R. Gallo
中科院分区:
--
文献类型:
--
作者:
R. Redfield;P. Markham;S. Salahuddin;D. Wright;M. Sarngadharan;R. Gallo

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在华盛顿特区沃尔特里德陆军医疗中心进行的顺序评估中,37%(15/41)的人类t细胞嗜淋巴病毒III型(HTLV-III)疾病(获得性免疫缺陷综合征[艾滋病]或艾滋病相关复合物)患者从异性伴侣处获得这种感染。这15名患者(10名男性和5名女性)的人口统计学特征与向疾病控制中心报告的患者有很大不同。6名患者被证实与患有艾滋病或有感染艾滋病风险的伴侣发生了异性性接触。其余9例患者有多个(大于50)异性伴侣和/或与妓女发生性接触。性行为的方式似乎与疾病获得无关;然而,这项研究清楚地表明,接受性肛交并不是必需的。本文报告的观察结果提供了进一步的流行病学证据,支持HTLV-III感染和疾病存在双向异性传播(男性与女性和女性与男性)。
Thirty-seven percent (15/41) of patients with human T-cell lymphotropic virus type III (HTLV-III) disease (acquired immunodeficiency syndrome [AIDS] or AIDS-related complex) sequentially evaluated at Walter Reed Army Medical Center, Washington, DC, acquired this infection from a partner(s) of the opposite sex. Demographic features of these 15 patients (ten males and five females) differed substantially from those for patients reported to the Centers for Disease Control. Heterosexual contact with partners who developed AIDS or who were at risk for AIDS was confirmed in six patients. The remaining nine patients had multiple (greater than 50) heterosexual partners and/or sexual contact with prostitutes. The method of sexual activity did not appear to be related to disease acquisition; however, this study clearly demonstrated that receptive anal intercourse was not a requirement. The observations reported herein provide further epidemiologic evidence to support the occurrence of bidirectional heterosexual transmission (both male to female and female to male) of HTLV-III infection and disease.
性乱和吸毒成瘾的母亲所生婴儿患有 T4/T8 比例逆转的获得性免疫缺陷。
DOI: --
发表时间: 1983
期刊: JAMA : the journal of the American Medical Association
影响因子: --
作者:
Rubinstein,A;Sicklick,M;Gupta,A;Bernstein,L;Klein,N;Rubinstein,E;Spigland,I;Fruchter,L;Litman,N;Lee,H;Hollander,M
通讯作者: Hollander,M
患有艾滋病相关综合症的人和有艾滋病风险的健康男同性恋者唾液中的 HTLV-III。
DOI: 10.1126/science.6093247
发表时间: 1984
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Groopman,JE;Salahuddin,SZ;Sarngadharan,MG;Markham,PD;Gonda,M;Sliski,A;Gallo,RC
通讯作者: Gallo,RC
患有获得性免疫缺陷综合症的男性女性性伴侣的免疫缺陷。
DOI: 10.1056/nejm198305193082001
发表时间: 1983
期刊: The New England journal of medicine
影响因子: --
作者:
Harris,C;Small,CB;Klein,RS;Friedland,GH;Moll,B;Emeson,EE;Spigland,I;Steigbigel,NH
通讯作者: Steigbigel,NH