Association of coronary dominance with the severity of coronary artery disease: a cross-sectional study in Shaanxi Province, China.
Association of coronary dominance with the severity of coronary artery disease: a cross-sectional study in Shaanxi Province, China.
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冠状动脉优势与冠状动脉疾病严重程度的关联：中国陕西省的一项横断面研究
DOI：
10.1136/bmjopen-2017-021292
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发表时间：
2018-11-08
期刊：
影响因子：
2.9
通讯作者：
Ma X
中科院分区：
文献类型：
--
作者：
Yan B;Yang J;Fan Y;Zhao B;Ma Q;Yang L;Ma X
目的探讨冠状动脉优势与冠状动脉病变程度的关系。设计横断面研究。设置单中心。在2015年7月至2017年2月期间，1654名接受冠状动脉造影（CAG）的患者被招募到这项横断面研究中。方法根据冠状动脉造影结果，将患者分为左优势（LD）、右优势（RD）和共优势（CD）。多元线性回归分析冠心病严重程度与冠状动脉优势的关系。结果RD组Gensini总分显著高于左侧CD组（42.3±33.6 vs 36.3±29.8; p=0.033）。校正潜在混杂因素后，多元线性回归结果显示RD与CAD严重程度相关（β=6.699，95%CI 1.193 - 12.205，p=0.017）。结论右冠状动脉优势与冠心病的严重程度有关。
Objective To investigate whether coronary artery dominance is associated with the severity of coronary artery disease (CAD). Design Cross-sectional study. Setting Single-centre. Participants Between July 2015 and February 2017, 1654 patients who underwent coronary angiography (CAG) were recruited into this cross-sectional study. Measurement and methods According to coronary dominance, patients were classified into left dominance (LD), right dominance (RD) and codominance (CD) based on the CAG results. Multiple linear regression analysis was performed to test the association between severity of CAD and coronary dominance. Results The total Gensini score was significantly higher in the RD group than in the left-CD group (42.3±33.6 vs 36.3±29.8; p=0.033). After adjusting for potential confounding factors, the results of multivariate linear regression showed that RD was associated with the severity of CAD (β=6.699, 95% CI 1.193 to 12.205, p=0.017). Conclusions The results suggest that right coronary dominance was associated with the severity of CAD.
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