Effects of operantly conditioning the amplitude of the P200 peak of the SEP on pain sensitivity and the spinal nociceptive withdrawal reflex in humans.

Effects of operantly conditioning the amplitude of the P200 peak of the SEP on pain sensitivity and the spinal nociceptive withdrawal reflex in humans.
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操作性调节 SEP P200 峰值幅度对人类疼痛敏感性和脊髓伤害性撤退反射的影响。

DOI:
10.1111/j.1469-8986.1996.tb00422.x
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发表时间:
1996
期刊:
影响因子:
3.7
通讯作者:
Dowman,R
Dowman,R
中科院分区:
心理学3区
文献类型:
--
作者:
Dowman,R

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本研究试图复制和扩展早期的研究,即当奖励取决于变化时,人类体感诱发电位(SEP)的P200峰值的振幅可以增加和减少,并且这些变化伴随着疼痛敏感性的改变。在增加训练(向上训练)期间,有21名受试者能够使腓肠神经刺激引起的P200峰值的振幅比减少训练(向下训练)时更大。上下训练时腓肠神经复合动作电位无差异。这一发现表明P200振幅的变化不是由于刺激效果的变化,而是由于中枢神经系统的变化。主观疼痛评分和伤害性脊柱反射在上训练和下训练中是相同的。因此,P200振幅的条件变化不会改变疼痛敏感性。
This study attempted to replicate and extend earlier work that reported that the amplitude of the P200 peak of the human somatosensory evoked potential (SEP) can be increased and decreased when reward is made contingent upon change and that these changes are accompanied by alterations in pain sensitivity. Twenty‐one subjects were able to make the amplitude of the P200 peak evoked by sural nerve stimulation larger during increased training (up‐training) than during decreased training (down‐training). There were no differences in the sural nerve compound action potential between up‐training and down‐training. This finding demonstrates that the change in P200 amplitude was not due to a change in stimulus efficacy, but rather to a change within the central nervous system. Subjective pain ratings and a nociceptive spinal reflex were the same in up‐training as in down‐training. Thus, conditioned changes in P200 amplitude do not alter pain sensitivity.
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发表时间: 1985
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