The immune system in pregnancy: a unique complexity.
The immune system in pregnancy: a unique complexity.
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DOI：
10.1111/j.1600-0897.2010.00836.x
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发表时间：
2010-06
期刊：
影响因子：
--
通讯作者：
Cardenas I
中科院分区：
文献类型：
--
作者：
Mor G;Cardenas I
胎盘免疫反应及其对特定病毒和病原体的趋向性影响孕妇对某些传染病的易感性和严重程度的结果。将怀孕普遍化为免疫抑制或风险增加的一种情况具有误导性，并妨碍确定在大流行期间治疗孕妇的适当准则。有必要评估每种特定病原体与胎儿/胎盘单位的相互作用及其反应，以设计适当的预防或治疗。多年来，妊娠免疫学的复杂性和对妊娠免疫学作为器官移植概念的关注使该领域复杂化，并推迟了具有临床意义的新指南的制定，这些指南可能有助于回答这些问题和其他相关问题。作为对生殖免疫学领域感兴趣的科学家和临床医生，我们面临的挑战是评估许多“经典概念”，以定义新的方法，以便更好地理解怀孕免疫学，从而在不同的临床情况下使母亲和胎儿受益。
Placental immune response and its tropism for specific viruses and pathogens affect the outcome of the pregnant woman’s susceptibility to and severity of certain infectious diseases. The generalization of pregnancy as a condition of immune suppression or increased risk is misleading and prevents the determination of adequate guidelines for treating pregnant women during pandemics. There is a need to evaluate the interaction of each specific pathogen with the fetal/placental unit and its responses to design the adequate prophylaxis or therapy. The complexity of the immunology of pregnancy and the focus, for many years, on the concept of immunology of pregnancy as an organ transplantation have complicated the field and delayed the development of new guidelines with clinical implications that could help to answer these and other relevant questions. Our challenge as scientists and clinicians interested in the field of reproductive immunology is to evaluate many of the ‘classical concepts’ to define new approaches for a better understanding of the immunology of pregnancy that will benefit mothers and fetuses in different clinical scenarios.
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DOI：
10.1111/j.1600-0897.2004.00156.x
发表时间：
2004-04-01
影响因子：
3.6
作者：
Abrahams, VM;Kim, YM;Mor, G
通讯作者：
Mor, G
影响因子：
15.3
作者：
Ashkar, A A;Di Santo, J P;Croy, B A
通讯作者：
Croy, B A
DOI：
10.1111/j.1600-0897.2009.00792.x
发表时间：
2010-01
期刊：
American journal of reproductive immunology (New York, N.Y. : 1989)
影响因子：
--
作者：
Dekel N;Gnainsky Y;Granot I;Mor G
通讯作者：
Mor G
影响因子：
82.9
作者：
Blois, Sandra M.;Ilarregui, Juan M.;Arck, Petra C.
通讯作者：
Arck, Petra C.
DOI：
10.1051/rnd:19881006
发表时间：
1988-01-01
期刊：
REPRODUCTION NUTRITION DEVELOPMENT
影响因子：
--
作者：
BULMER, JN;PACE, D;RITSON, A
通讯作者：
RITSON, A