Magnetic Resonance Imaging Characteristics of Primary Intraspinal Peripheral Primitive Neuroectodermal Tumour
Magnetic Resonance Imaging Characteristics of Primary Intraspinal Peripheral Primitive Neuroectodermal Tumour
复制标题
原发性椎管内周围原始神经外胚层肿瘤的磁共振成像特征
DOI：
10.1016/j.carj.2012.01.001
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发表时间：
2013-08
期刊：
影响因子：
--
通讯作者：
Su, Jiajia
中科院分区：
文献类型：
--
作者：
Ghimire, Prasanna;Zhu, Ling;Baral, Aparajita;Su, Jiajia
目的本研究的目的是描述原发性椎管内周围原始神经外胚层肿瘤（PNET）的磁共振成像（MRI）表现。方法对7例经病理证实的椎管内周围原始神经外胚层肿瘤的临床和MRI图像进行回顾性分析。各种参数，例如椎体受累程度；肿瘤位置、大小、病灶性和边缘；病变的信号强度；是否存在出血或钙化；任何信号空白；评估邻近脐带的脐带受压情况；脐带扩张；椎旁组织肿块的存在；或椎骨或其他骨骼变化进行分析。结果所有7例患者的胸腰段均有病变。 3例患者出现硬膜外病变，4例患者出现硬膜内髓外病变，无髓内病变。六个病灶边界清楚。仅 1 名患者出现多灶性受累。所有病灶在 T1 加权成像上均为低信号或等信号，而除一个以外的所有病灶在 T2 加权成像上均为高信号。除1个硬膜内髓外病灶均匀强化外，病灶强化不均匀。 2 名患者发现椎旁肿块。 1例患者出现椎体塌陷。结论椎管内周围型PNETs是罕见的脊柱肿瘤。尽管影像学特征并不具体，但年轻个体位于髓内、髓外硬膜内或硬膜外脊柱位置的局灶性局限性病变在 T1 和 T2 加权图像上分别显示低信号和高信号，需要在差异中考虑 PNET。
PurposeThe purpose of our study was to describe the salient magnetic resonance imaging (MRI) findings in primary intraspinal peripheral primitive neuroectodermal tumour (PNET).MethodsA retrospective review of the clinical and MRI images of 7 pathologically proven cases of intraspinal peripheral PNETs was performed. The various parameters, such as vertebral level of involvement; tumour location, size, focality, and margin; signal intensity of the lesion; the presence of hemorrhage or calcification; any signal voids; assessment of the adjacent cord for cord compression; cord dilatation; the presence of paraspinal tissue mass; or vertebral or other bony changes, were analysed.ResultsAll 7 patients had lesions in the thoracolumbar region. Three patients had extradural lesions, 4 had intradural extramedullary lesions, and none had intramedullary lesions. Six lesions were well circumscribed. Only 1 patient had multifocal involvement. All lesions were of hypointense or isointense signal on T1-weighted imaging, whereas all but one were hyperintense on T2-weighted imaging. Lesions enhanced heterogeneously except 1 intradural extramedullary lesion, which enhanced homogeneously. A paraspinal mass was noticed in 2 patients. Vertebral collapse was present in 1 patients.ConclusionIntraspinal peripheral PNETs are rare spinal tumours. Although imaging characteristics are not specific, a focal circumscribed lesion in a young individual at the intramedullary, extramedullary intradural, or extradural spinal location that shows hypointense and hyperintense signal on T1- and T2-weighted images, respectively, requires PNET to be considered in the differentials.
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影响因子：
3.4
作者：
L. Granowetter
通讯作者：
L. Granowetter
DOI：
10.1016/0149-936x(87)90071-3
发表时间：
1987-10
期刊：
The Journal of computed tomography
影响因子：
--
作者：
Hon-Man Liu;Wen C. Yang;Roger L. Garcia;Jae M. Noh;Vidya Malhotra;Norman E. Leeds
通讯作者：
Hon-Man Liu;Wen C. Yang;Roger L. Garcia;Jae M. Noh;Vidya Malhotra;Norman E. Leeds
影响因子：
3.3
作者：
Duan, Xiao-Hui;Ban, Xiao-Hua;Shen, Jun
通讯作者：
Shen, Jun
影响因子：
4.2
作者：
Koga, Hideyuki;Matsumoto, Seiichi;Kawaguchi, Noriyoshi
通讯作者：
Kawaguchi, Noriyoshi
影响因子：
4.2
作者：
H. Koga;S. Matsumoto;J. Manabe;T. Tanizawa;N. Kawaguchi
通讯作者：
H. Koga;S. Matsumoto;J. Manabe;T. Tanizawa;N. Kawaguchi