The Rat Genome Database 2013--data, tools and users.

The Rat Genome Database 2013--data, tools and users.
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DOI:
10.1093/bib/bbt007
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发表时间:
2013-07
影响因子:
9.5
通讯作者:
Jacob HJ
Jacob HJ
中科院分区:
生物学2区
文献类型:
--
作者:
Laulederkind SJ;Hayman GT;Wang SJ;Smith JR;Lowry TF;Nigam R;Petri V;de Pons J;Dwinell MR;Shimoyama M;Munzenmaier DH;Worthey EA;Jacob HJ

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大鼠基因组数据库(RGD)于10年前启动,为大鼠研究人员提供核心基因组资源。目前,RGD结合了遗传、基因组、途径、表型和品系信息,重点关注疾病。RGD用户可以访问从分子水平到组织水平的结构化和精心策划的数据。这些用户从世界各地访问RGD。最终用户不仅是大鼠研究人员,还包括研究小鼠和人类数据的研究人员。RGD在疾病门户网站、GBrowse、VCMap和基因报告页面上的比较遗传学/基因组学数据支持转化研究。RGD的影响也超越了传统的生物医学研究人员,因为RGD的影响达到了生物信息学家、工具开发人员和策展人。将RGD数据导入其他公开可用的数据库,将扩大RGD对更多最终用户的影响,而不是那些利用RGD网站的用户。随着更多类型的数据和工具的加入,RGD的价值持续增长,同时触及更多类型的最终用户。
The Rat Genome Database (RGD) was started >10 years ago to provide a core genomic resource for rat researchers. Currently, RGD combines genetic, genomic, pathway, phenotype and strain information with a focus on disease. RGD users are provided with access to structured and curated data from the molecular level through the organismal level. Those users access RGD from all over the world. End users are not only rat researchers but also researchers working with mouse and human data. Translational research is supported by RGD’s comparative genetics/genomics data in disease portals, in GBrowse, in VCMap and on gene report pages. The impact of RGD also goes beyond the traditional biomedical researcher, as the influence of RGD reaches bioinformaticians, tool developers and curators. Import of RGD data into other publicly available databases expands the influence of RGD to a larger set of end users than those who avail themselves of the RGD website. The value of RGD continues to grow as more types of data and more tools are added, while reaching more types of end users.
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