The timing of adrenarche in Maya girls, Merida, Mexico.
The timing of adrenarche in Maya girls, Merida, Mexico.
复制标题
玛雅女孩肾上腺初长的时间，梅里达，墨西哥。
DOI：
10.1002/ajhb.23465
复制
发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Varela-Silva MI
中科院分区：
文献类型：
--
作者：
Keestra SM;Bentley GR;Núñez-de la Mora A;Houghton LC;Wilson H;Vázquez-Vázquez A;Cooper GD;Dickinson F;Griffiths P;Bogin BA;Varela-Silva MI
肾上腺初显涉及下丘脑-垂体-肾上腺轴的成熟和脱氢表雄酮及其硫酸酯，脱氢表雄酮硫酸酯（DHEA-S）的产生增加。它发生在工业化人口的6至8岁，标志着从童年到青少年的过渡和童年中期的认知发展。在维持生计水平人群中的研究表明，肾上腺初发年龄较晚（8 - 9岁），但目前只有两项此类研究可供比较。研究玛雅女孩的肾上腺年龄及其与身体成分和饮食变量的关系。我们假设肾上腺初显会发生在墨西哥目前的双重营养负担。来自墨西哥梅里达的25名7至9岁的玛雅女孩，使用ELISA测量唾液DHEA-S，身高，体重和皮褶的标准人体测量，身体成分变量的生物电阻抗，以及饮食信息的食物频率问卷。我们的假设被拒绝-肾上腺初显发生在接近9年。虽然没有身体成分的测量与肾上腺素状态显着相关，但更经常吃肉和奶制品的女孩有显着更高的DHEA-S水平。与其他生活在生态环境恶劣的人群一样，玛雅女孩的肾上腺素初发相对较晚。肾上腺初显与身体成分的测量有关，特别是肥胖或体重指数反弹，但可能是因为样本量小，没有相关的人体测量。需要进一步的研究来阐明肾上腺素变化与其他过渡人群的发育可塑性、身体组成、青春期进展和动物产品消费之间的关系。
Adrenarche involves maturation of the hypothalamic‐pituitary‐adrenal axis and increased production of dehydroepiandrosterone and its sulfate ester, dehydroepiandrosterone‐sulfate (DHEA‐S). It occurs at ages 6 to 8 in industrialized populations, marking the transition from childhood to juvenility and cognitive development at middle childhood. Studies in subsistence level populations indicate a later age (8‐9) for adrenarche, but only two such studies currently exist for comparison. To investigate adrenarcheal age among Maya girls and its association with body composition and dietary variables. We hypothesized adrenarche would occur earlier given the current dual burden of nutrition in Mexico. 25 Maya girls aged 7 to 9 from Merida, Mexico using ELISAs to measure salivary DHEA‐S, standard anthropometry for height, weight, and skinfolds, bioelectrical impedance for body composition variables, as well as a food frequency questionnaire for dietary information. Our hypothesis was rejected—adrenarche occurred close to 9 years. While no measures of body composition were significantly associated with adrenarcheal status, girls eating meat and dairy products more frequently had significantly higher DHEA‐S levels. Like other populations living in ecologically challenging environments, adrenarche occurred relatively late among Maya girls. Adrenarche has been linked to measures of body composition, particularly, the adiposity or body mass index rebound, but no relevant anthropometric measures were associated, possibly because of the small sample. Further studies are required to illuminate how adrenarcheal variation relates to developmental plasticity, body composition, pubertal progression, and animal product consumption in other transitional populations.
登录
查看更多内容
影响因子：
3.7
作者：
Houghton LC;Cooper GD;Booth M;Chowdhury OA;Troisi R;Ziegler RG;Katki HA;Hoover RN;Bentley GR
通讯作者：
Bentley GR
影响因子：
4.7
作者：
Ramirez, E.;Valencia, M. E.;Aleman-Mateo, H.
通讯作者：
Aleman-Mateo, H.
影响因子：
7.4
作者：
Maninger, Nicole;Wolkowitz, Owen M.;Reus, Victor I.;Epel, Elissa S.;Mellon, Synthia H.
通讯作者：
Mellon, Synthia H.
影响因子：
4.9
作者：
McCarthy, HD;Cole, TJ;Prentice, AM
通讯作者：
Prentice, AM
影响因子：
4.9
作者：
PETERSEN, AC;CROCKETT, L;BOXER, A
通讯作者：
BOXER, A