The evolution of metazoan extracellular matrix.
The evolution of metazoan extracellular matrix.
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DOI:
10.1083/jcb.201109041
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发表时间:
2012-03-19
期刊:
影响因子:
--
通讯作者:
Hynes RO
中科院分区:
文献类型:
--
作者:
Hynes RO
The modular domain structure of extracellular matrix (ECM) proteins and their genes has allowed extensive exon/domain shuffling during evolution to generate hundreds of ECM proteins. Many of these arose early during metazoan evolution and have been highly conserved ever since. Others have undergone duplication and divergence during evolution, and novel combinations of domains have evolved to generate new ECM proteins, particularly in the vertebrate lineage. The recent sequencing of several genomes has revealed many details of this conservation and evolution of ECM proteins to serve diverse functions in metazoa.
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影响因子:
3.7
作者:
Gazave E;Lapébie P;Renard E;Vacelet J;Rocher C;Ereskovsky AV;Lavrov DV;Borchiellini C
通讯作者:
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DOI:
10.1126/science.1176009
发表时间:
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期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Hynes RO
通讯作者:
Hynes RO
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