Evolutionary Dynamics and Epidemiology of Endemic and Emerging Coronaviruses in Humans, Domestic Animals, and Wildlife.

Evolutionary Dynamics and Epidemiology of Endemic and Emerging Coronaviruses in Humans, Domestic Animals, and Wildlife.
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DOI:
10.3390/v13101908
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发表时间:
2021-09-23
期刊:
Viruses
影响因子:
--
通讯作者:
Shirin T
Shirin T
中科院分区:
其他
文献类型:
--
作者:
Islam A;Ferdous J;Islam S;Sayeed MA;Dutta Choudhury S;Saha O;Hassan MM;Shirin T

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不同的冠状病毒(CoV)菌株可以感染人类和动物,并产生各种疾病。在过去的二十年里,CoV已经引起了三次流行病和大流行,并对公共卫生和全球经济造成了严重影响。因此,了解人类和动物中地方性和新兴CoV多样性的出现和演变至关重要。对于不同的鸟类物种,传染性支气管炎病毒是一个重要的,而猫肠道和犬冠状病毒,重组产生猫传染性腹膜炎病毒,感染野猫。牛和犬的冠状病毒具有祖先关系,而猪的冠状病毒,特别是SADS-CoV,可以跨越物种障碍。蝙蝠被认为是多种甲型和乙型冠状病毒株的天然宿主。虽然MERS CoV对骆驼和人类都很重要,但人类受到的影响更严重。自2012年以来,中东呼吸综合征冠状病毒病例主要在阿拉伯半岛报告。到目前为止,已有7种CoV病毒感染了人类,它们都是动物的后代。严重急性呼吸综合征冠状病毒(SARS-CoV和SARS-CoV-2)被认为起源于严重感染人类并扩散到多种家畜和野生动物的鼻蝠。在宠物和野生动物中检测到SARS-CoV-2的新出现的α和δ变体。尽管如此,中间宿主和所有易感动物物种仍然未知。SARS-CoV-2可能不是最后一个跨越物种屏障的CoV。因此,我们建议为人类开发一种通用的CoV疫苗,以便有效预防未来的任何爆发。此外,应在人-动物接触面实施“一个健康”的冠状病毒监测方法,以在新型冠状病毒出现在人类身上之前检测出新型冠状病毒,并预防未来的流行病和大流行病。
Diverse coronavirus (CoV) strains can infect both humans and animals and produce various diseases. CoVs have caused three epidemics and pandemics in the last two decades, and caused a severe impact on public health and the global economy. Therefore, it is of utmost importance to understand the emergence and evolution of endemic and emerging CoV diversity in humans and animals. For diverse bird species, the Infectious Bronchitis Virus is a significant one, whereas feline enteric and canine coronavirus, recombined to produce feline infectious peritonitis virus, infects wild cats. Bovine and canine CoVs have ancestral relationships, while porcine CoVs, especially SADS-CoV, can cross species barriers. Bats are considered as the natural host of diverse strains of alpha and beta coronaviruses. Though MERS-CoV is significant for both camels and humans, humans are nonetheless affected more severely. MERS-CoV cases have been reported mainly in the Arabic peninsula since 2012. To date, seven CoV strains have infected humans, all descended from animals. The severe acute respiratory syndrome coronaviruses (SARS-CoV and SARS-CoV-2) are presumed to be originated in Rhinolopoid bats that severely infect humans with spillover to multiple domestic and wild animals. Emerging alpha and delta variants of SARS-CoV-2 were detected in pets and wild animals. Still, the intermediate hosts and all susceptible animal species remain unknown. SARS-CoV-2 might not be the last CoV to cross the species barrier. Hence, we recommend developing a universal CoV vaccine for humans so that any future outbreak can be prevented effectively. Furthermore, a One Health approach coronavirus surveillance should be implemented at human-animal interfaces to detect novel coronaviruses before emerging to humans and to prevent future epidemics and pandemics.
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