Ionic and electrophysiological properties of retinal Müller (glial) cells of the turtle.
Ionic and electrophysiological properties of retinal Müller (glial) cells of the turtle.
复制标题
乌龟视网膜穆勒（神经胶质）细胞的离子和电生理特性。
DOI：
10.1113/jphysiol.1985.sp015664
复制
发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Sarthy,PV
中科院分区：
文献类型：
--
作者：
Conner,JD;Detwiler,PB;Sarthy,PV
研究了脊椎动物视网膜的主要神经胶质细胞穆勒细胞的离子和电生理特性。酶解原位 Müller 细胞的膜电位约为 ‐80 mV，并且依赖于外部 K+ 浓度，其方式由 Goldman-Hodgkin-Katz 方程描述，Na+-K+ 渗透率比为 0.037。电流-电压关系显示出明显的内向整流，静息电位下的输入电阻对于离解细胞约为 30 M Ω，对于原位细胞约为 3 M Ω。发现原位穆勒电池彼此电耦合，这可以解释它们的较低电阻。我们得出的结论是，穆勒细胞与其他类型的神经胶质细胞相似。尽管 Na+ 渗透性有限，但它们的膜电位主要由 K+ 决定，但它们是电不可兴奋的，并在视网膜中形成电耦合网络。
The ionic and electrophysiological properties of Müller cells, the principal glial element of the vertebrate retina, were investigated. The membrane potential of enzymatically dissociated and in situ Müller cells was about ‐80 mV and depended on external K+ concentration in a manner that was described by the Goldman‐Hodgkin‐Katz equation with a Na+‐K+ permeability ratio of 0.037. The current‐voltage relation showed marked inward rectification, with the input resistance at the resting potential being about 30 M omega for dissociated cells and about 3 M omega for in situ cells. In situ Müller cells were found to be electrically coupled to each other which could explain their lower resistance. We conclude that Müller cells are similar to other types of glia. In spite of a finite Na+ permeability their membrane potential is determined mainly by K+, they are electrically inexcitable and form an electrically coupled network in the retina.
登录
查看更多内容
钾离子和氯离子对小龙虾单肌纤维膜电位的影响
DOI：
10.1016/0300-9629(71)90160-5
发表时间：
1971
期刊：
Comparative biochemistry and physiology. A, Comparative physiology
影响因子：
--
作者：
Maija Hinkle;Philip Heller;W. G. V. D. Kloot
通讯作者：
W. G. V. D. Kloot
人类神经胶质细胞的电生理特性
影响因子：
15.9
作者：
Selwyn Picker
通讯作者：
Selwyn Picker
影响因子：
2.9
作者：
KARWOSKI, CJ;PROENZA, LM
通讯作者：
PROENZA, LM
从海龟视网膜中分离出的神经胶质（穆勒）细胞的生化研究
影响因子：
7.8
作者：
P. Sarthy;D. Lam
通讯作者：
D. Lam
神经胶质细胞的电生理学。
影响因子：
18.2
作者：
G. Somjen
通讯作者：
G. Somjen