Prenatal exposure to ambient air temperature and risk of early delivery.
Prenatal exposure to ambient air temperature and risk of early delivery.
复制标题
DOI：
10.1016/j.envint.2020.105824
复制
发表时间：
2020-09
影响因子：
11.8
通讯作者：
Raz R
中科院分区：
文献类型：
--
作者：
Spolter F;Kloog I;Dorman M;Novack L;Erez O;Raz R
早产是不利健康后果的一个主要决定因素，早产也与各种后果的风险增加有关。考虑到气候变化，环境温度对提前交货的影响是一个重要的考虑因素。一些研究集中在环境空气温度（Ta）与早产的关系，但很少有研究与早产的关系。研究半干旱气候下产前暴露于Ta与早产（< 37妊娠周）和早产（< 39妊娠周）的关系。以色列南区索罗卡医疗中心所有估计受孕日期在2004年5月1日至2013年3月31日之间的单胎分娩（N=62,547）均与根据每日1公里分辨率的时空分辨率模型估算的产前Ta相关联。我们使用时间相关的Cox回归模型，在整个妊娠期采用周平均Ta，并根据受孕月份和年份、种族、人口普查水平的社会经济状况和人口密度进行调整。Ta与晚期早产（31+0/7 - 36+6/7周）呈正相关，与第三个五分位数相比，Ta上五分位数的风险增加，风险比(HR) = 1.31, 95%置信区间(CI) = 1.11−1.56。Ta也与早产有关（37+0/6 - 38+6/7），与第三个五分位数相比，Ta上五分位数的风险增加，HR = 1.24, 95% CI = 1.13 - 1.36。在以色列南部，怀孕期间暴露在高温环境中与早产和早产的风险较高有关。
Preterm birth is a major determinant of adverse health consequences, and early term births are also associated with increased risk of various outcomes. In light of climate change, the effect of ambient temperature on earlier delivery is an important factor to consider. Several studies have focused on associations of ambient air temperature (Ta) on preterm birth, but few have examined associations with early term births. To investigate the association of prenatal exposure to Ta with preterm birth (< 37 completed gestation weeks) and with early-term birth (< 39 completed gestation weeks) in a semi-arid climate. All singleton deliveries at the Soroka Medical Center from the Southern district of Israel, with estimated conception dates between May 1, 2004 and March 31, 2013 (N=62,547) were linked to prenatal Ta estimates from a spatiotemporally resolved model, with daily 1 km resolution. We used time-dependent Cox regression models with weekly mean Ta throughout gestation, adjusted for calendar month and year of conception, ethnicity, census-level socio-economic status and population density. Ta was positively associated with late preterm birth (31+0/7 – 36+6/7 weeks), with increased risk in the upper Ta quintile as compared to the third quintile, hazard ratio (HR) = 1.31, 95% confidence interval (CI) = 1.11 −1.56. Ta also associated with early term birth (37+0/6 – 38+6/7), with increased risk in the upper Ta quintile as compared to the third quintile, HR = 1.24, 95% CI = 1.13 – 1.36. Exposure to high ambient temperature during pregnancy is associated with a higher risk of preterm and early term birth in southern Israel.
登录
查看更多内容
影响因子：
8.3
作者：
Ha S;Zhu Y;Liu D;Sherman S;Mendola P
通讯作者：
Mendola P
影响因子：
7.7
作者：
Liew, Zeyan;Olsen, Jorn;Arah, Onyebuchi A.
通讯作者：
Arah, Onyebuchi A.
影响因子：
6.7
作者：
Fukuda, Misao;Fukuda, Kiyomi;Andersen, Claus Yding
通讯作者：
Andersen, Claus Yding
影响因子：
2.9
作者：
Catalano, R.;Yorifuji, T.;Kawachi, I.
通讯作者：
Kawachi, I.
影响因子：
10.4
作者：
Ha S;Liu D;Zhu Y;Kim SS;Sherman S;Mendola P
通讯作者：
Mendola P