Life expectancy and death by diseases of the circulatory system in patients with bipolar disorder or schizophrenia in the Nordic countries.
Life expectancy and death by diseases of the circulatory system in patients with bipolar disorder or schizophrenia in the Nordic countries.
复制标题
DOI：
10.1371/journal.pone.0067133
复制
发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Nordentoft M
中科院分区：
文献类型：
--
作者：
Laursen TM;Wahlbeck K;Hällgren J;Westman J;Ösby U;Alinaghizadeh H;Gissler M;Nordentoft M
有大量报告指出，精神障碍患者因疾病和医疗状况（自然死亡）而死亡率过高。即使在福利制度发达的北欧国家，基于登记的研究也发现了死亡率过高的证据。近年来，所有北欧国家的心源性死亡率和循环系统疾病死亡率都有所下降，但最近的一篇论文表明，丹麦、芬兰和瑞典的女性和男性因精神障碍住院治疗，死于心血管疾病的风险增加了两到三倍。本研究的目的是比较三个北欧国家丹麦、瑞典和芬兰的双相情感障碍或精神分裂症患者的循环系统疾病死亡率。此外，目的是检查和比较这些患者的预期寿命。计算每个特定死亡亚组的特定原因标准化死亡率（SMR）。使用Wiesler方法计算预期寿命。在所有国家和两种性别中，双相情感障碍循环系统疾病的SMR约为2。除了丹麦的男性外，所有国家的精神分裂症患者的SMR都略高。双相情感障碍或精神分裂症患者的总体预期寿命要低得多，预期寿命短11至20年。我们的数据表明，北欧国家的精神分裂症或双相情感障碍患者的预期寿命大大缩短。在规划未来几年的医疗保健时，应优先评估这些死亡率增加的原因。
Excess mortality from diseases and medical conditions (natural death) in persons with psychiatric disorders has been extensively reported. Even in the Nordic countries with well-developed welfare systems, register based studies find evidence of an excess mortality. In recent years, cardiac mortality and death by diseases of the circulatory system has seen a decline in all the Nordic countries, but a recent paper indicates that women and men in Denmark, Finland, and Sweden, who had been hospitalised for a psychotic disorder, had a two to three-fold increased risk of dying from a cardiovascular disease. The aim of this study was to compare the mortality by diseases of the circulatory system among patients with bipolar disorder or schizophrenia in the three Nordic countries Denmark, Sweden, and Finland. Furthermore, the aim was to examine and compare life expectancy among these patients. Cause specific Standardized Mortality Rates (SMRs) were calculated for each specific subgroup of mortality. Life expectancy was calculated using Wiesler’s method. The SMR for bipolar disorder for diseases of the circulatory system was approximately 2 in all countries and both sexes. SMR was slightly higher for people with schizophrenia for both genders and in all countries, except for men in Denmark. Overall life expectancy was much lower among persons with bipolar disorder or schizophrenia, with life expectancy being from 11 to 20 years shorter. Our data show that persons in the Nordic countries with schizophrenia or bipolar disorder have a substantially reduced life expectancy. An evaluation of the reasons for these increased mortality rates should be prioritized when planning healthcare in the coming years.
登录
查看更多内容
影响因子：
10.5
作者：
Joukamaa, M;Heliövaara, M;Lehtinen, V
通讯作者：
Lehtinen, V
影响因子：
4.8
作者：
Hennekens, CH;Hennekens, AR;Casey, DE
通讯作者：
Casey, DE
影响因子：
4.5
作者：
Angst, J
通讯作者：
Angst, J
影响因子：
--
作者：
Laursen, Thomas Munk;Munk-Olsen, Trine;Mortensen, Preben Bo
通讯作者：
Mortensen, Preben Bo
影响因子：
4.8
作者：
Laursen, Thomas Munk;Nordentoft, Merete
通讯作者：
Nordentoft, Merete