Insomnia, Poor Sleep Quality and Sleep Duration, and Risk for COVID-19 Infection and Hospitalization.
Insomnia, Poor Sleep Quality and Sleep Duration, and Risk for COVID-19 Infection and Hospitalization.
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DOI：
10.1016/j.amjmed.2023.04.002
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发表时间：
2023-08
影响因子：
5.9
通讯作者：
Czeisler, Charles A.
中科院分区：
文献类型：
--
作者：
Quan, Stuart F.;Weaver, Matthew D.;Czeisler, Mark E.;Barger, Laura K.;Booker, Lauren A.;Howard, Mark E.;Jackson, Melinda L.;Lane, Rashon I.;McDonald, Christine F.;Ridgers, Anna;Robbins, Rebecca;Varma, Prerna;Wiley, Joshua F.;Rajaratnam, Shantha M. W.;Czeisler, Charles A.
医疗合并症增加了COVID-19严重急性疾病的风险。虽然睡眠问题在COVID-19感染后很常见，但目前尚不清楚失眠、睡眠质量差、睡眠过长或过短是否会增加感染COVID-19或住院的风险。该研究对19926名美国成年人的不同样本进行了横断面调查。新冠肺炎感染率和住院率分别为40.1%和2.9%。失眠和睡眠质量差的比例分别为19.8%和40.1%。在排除报告与COVID-19相关睡眠问题的参与者的合并症医疗条件和睡眠时间调整后的logistic回归模型中，睡眠质量差（但不包括失眠）与COVID-19感染（调整优势比[aOR] 1.16; 95% CI, 1.07-1.26）和COVID-19住院（aOR 1.50; 95% CI, 1.18-1.91）相关。与7-8小时的习惯睡眠时间相比，睡眠时间<7小时（aOR 1.14; 95% CI, 1.06-1.23）和睡眠时间为12小时（aOR 1.61; 95% CI, 1.12-2.31）与COVID-19感染几率增加相关。总体而言，COVID-19感染与睡眠时间之间的关系呈二次型（u型）模式。没有观察到睡眠时间与COVID-19住院之间的关联。在一般人群样本中，睡眠质量差和睡眠时间过长与感染COVID-19的几率增加有关；睡眠质量差与COVID-19重症住院需求增加有关。这些观察结果表明，将健康睡眠习惯纳入公共卫生信息可能会减少COVID-19大流行的影响。
Medical comorbidities increase the risk of severe acute COVID-19 illness. Although sleep problems are common after COVID-19 infection, it is unclear whether insomnia, poor sleep quality, and extremely long or short sleep increase risk of developing COVID-19 infection or hospitalization. The study used a cross-sectional survey of a diverse sample of 19,926 US adults. COVID-19 infection and hospitalization prevalence rates were 40.1% and 2.9%, respectively. Insomnia and poor sleep quality were reported in 19.8% and 40.1%, respectively. In logistic regression models adjusted for comorbid medical conditions and sleep duration but excluding participants who reported COVID-19-associated sleep problems, poor sleep quality, but not insomnia, was associated with COVID-19 infection (adjusted odds ratio [aOR] 1.16; 95% CI, 1.07-1.26) and COVID-19 hospitalization (aOR 1.50; 95% CI, 1.18-1.91). In comparison with habitual sleep duration of 7-8 hours, sleep durations <7 hours (aOR 1.14; 95% CI, 1.06-1.23) and sleep duration of 12 hours (aOR 1.61; 95% CI, 1.12-2.31) were associated with increased odds of COVID-19 infection. Overall, the relationship between COVID-19 infection and hours of sleep followed a quadratic (U-shaped) pattern. No association between sleep duration and COVID-19 hospitalization was observed. In a general population sample, poor sleep quality and extremes of sleep duration are associated with greater odds of having had a COVID-19 infection; poor sleep quality was associated with an increased requirement of hospitalization for severe COVID-19 illness. These observations suggest that inclusion of healthy sleep practices in public health messaging may reduce the impact of the COVID-19 pandemic.
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DOI：
10.15585/mmwr.mm6915e3
发表时间：
2020-04-17
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Garg S;Kim L;Whitaker M;O'Halloran A;Cummings C;Holstein R;Prill M;Chai SJ;Kirley PD;Alden NB;Kawasaki B;Yousey-Hindes K;Niccolai L;Anderson EJ;Openo KP;Weigel A;Monroe ML;Ryan P;Henderson J;Kim S;Como-Sabetti K;Lynfield R;Sosin D;Torres S;Muse A;Bennett NM;Billing L;Sutton M;West N;Schaffner W;Talbot HK;Aquino C;George A;Budd A;Brammer L;Langley G;Hall AJ;Fry A
通讯作者：
Fry A
影响因子：
13.8
作者：
Ioannou GN;Locke E;Green P;Berry K;O'Hare AM;Shah JA;Crothers K;Eastment MC;Dominitz JA;Fan VS
通讯作者：
Fan VS
影响因子：
82.9
作者：
Furman, David;Campisi, Judith;Slavich, George M.
通讯作者：
Slavich, George M.
影响因子：
4.3
作者：
Mashaqi, Saif;Lee-Iannotti, Joyce;Parthasarathy, Sairam
通讯作者：
Parthasarathy, Sairam
影响因子：
11.3
作者：
BUYSSE, DJ;REYNOLDS, CF;KUPFER, DJ
通讯作者：
KUPFER, DJ