RAB11-mediated trafficking in host-pathogen interactions.
RAB11-mediated trafficking in host-pathogen interactions.
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DOI：
10.1038/nrmicro3325
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发表时间：
2014-09
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影响因子：
--
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文献类型：
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Many bacterial and viral pathogens block or subvert host cellular processes to promote successful infection. One host protein that is targeted by invading pathogens is the small GTPase RAB11, which functions in vesicular trafficking. RAB11 functions in conjunction with a protein complex known as the exocyst to mediate terminal steps in cargo transport via the recycling endosome to cell–cell junctions, phagosomes and cellular protrusions. These processes contribute to host innate immunity by promoting epithelial and endothelial barrier integrity, sensing and immobilizing pathogens and repairing pathogen-induced cellular damage. In this Review, we discuss the various mechanisms that pathogens have evolved to disrupt or subvert RAB11-dependent pathways as part of their infection strategy.
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DOI：
10.1084/jem.20091990
发表时间：
2010-03-15
期刊：
The Journal of experimental medicine
影响因子：
--
作者：
Gibb DR;El Shikh M;Kang DJ;Rowe WJ;El Sayed R;Cichy J;Yagita H;Tew JG;Dempsey PJ;Crawford HC;Conrad DH
通讯作者：
Conrad DH
DOI：
10.1073/pnas.2434327100
发表时间：
2003-12-09
影响因子：
11.1
作者：
Brock, SC;Goldenring, JR;Crowe, JE
通讯作者：
Crowe, JE
影响因子：
64.5
作者：
Chien, Yuchen;Kim, Sungchan;White, Michael A.
通讯作者：
White, Michael A.
影响因子：
3.1
作者：
Carbonetti NH
通讯作者：
Carbonetti NH
影响因子：
30.3
作者：
Guichard A;Cruz-Moreno B;Aguilar B;van Sorge NM;Kuang J;Kurkciyan AA;Wang Z;Hang S;Pineton de Chambrun GP;McCole DF;Watnick P;Nizet V;Bier E
通讯作者：
Bier E