The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes.
The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes.
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DOI：
10.1007/s00125-010-1927-1
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发表时间：
2011-02
期刊：
影响因子：
8.2
通讯作者：
Leiter, L. A.
中科院分区：
文献类型：
--
作者：
Jenkins, D. J. A.;Srichaikul, K.;Kendall, C. W. C.;Sievenpiper, J. L.;Abdulnour, S.;Mirrahimi, A.;Meneses, C.;Nishi, S.;He, X.;Lee, S.;So, Y. T.;Esfahani, A.;Mitchell, S.;Parker, T. L.;Vidgen, E.;Josse, R. G.;Leiter, L. A.
关键词：
糖被认为会导致肥胖、糖尿病和冠心病 (CHD)，但水果尽管含有糖，但血糖生成指数 (GI) 也可能较低，因此一般建议所有水果都有益健康。因此，我们评估了水果的影响，特别强调低 GI 水果摄入量对 2 型糖尿病的影响。这项二次分析涉及 152 名接受降糖药物治疗的 2 型糖尿病参与者，他们在平行设计中完成了 6 个月的高纤维或低 GI 饮食建议，包括水果建议。低GI水果摄入量的变化范围为-3.1至2.7份/天。低GI水果摄入量的增加显着预测HbA1c（r = −0.206，p = 0.011）、收缩压（r = −0.183，p = 0.024）和CHD风险（r = −0.213，p = −0.213， p = 0.008)。水果总摄入量的变化范围为-3.7 至 3.2 份/天，与研究结果无关。在包含低 GI 饮食中强调的八种主要碳水化合物食物或食物类别的回归分析中，只有低 GI 水果和面包对预测 HbA1c 变化有独立且显着的贡献。此外，比较低 GI 水果摄入量的最高和最低四分位数，HbA1c 的百分比变化降低了 -0.5% HbA1c 单位（95% CI 0.2–0.8 HbA1c 单位，p<<0.001）。作为低 GI 饮食一部分的低 GI 水果摄入量与较低的 HbA1c、血压和 CHD 风险相关，并支持低 GI 水果摄入量在 2 型糖尿病管理中的作用。 ClinicalTrials.gov NCT00438698 加拿大健康研究所；加拿大联邦政府、Loblaw Companies 和 Barilla（意大利）捐赠基金的加拿大研究主席。本文的在线版本 (doi:10.1007/s00125-010-1927-1) 包含补充材料，可供授权用户使用。
Sugar has been suggested to promote obesity, diabetes and coronary heart disease (CHD), yet fruit, despite containing sugars, may also have a low glycaemic index (GI) and all fruits are generally recommended for good health. We therefore assessed the effect of fruit with special emphasis on low GI fruit intake in type 2 diabetes. This secondary analysis involved 152 type 2 diabetic participants treated with glucose-lowering agents who completed either 6 months of high fibre or low GI dietary advice, including fruit advice, in a parallel design. Change in low GI fruit intake ranged from −3.1 to 2.7 servings/day. The increase in low GI fruit intake significantly predicted reductions in HbA1c (r = −0.206, p = 0.011), systolic blood pressure (r = −0.183, p = 0.024) and CHD risk (r = −0.213, p = 0.008). Change in total fruit intake ranged from −3.7 to 3.2 servings/day and was not related to study outcomes. In a regression analysis including the eight major carbohydrate foods or classes of foods emphasised in the low GI diet, only low GI fruit and bread contributed independently and significantly to predicting change in HbA1c. Furthermore, comparing the highest with the lowest quartile of low GI fruit intake, the percentage change in HbA1c was reduced by −0.5% HbA1c units (95% CI 0.2–0.8 HbA1c units, p < 0.001). Low GI fruit consumption as part of a low GI diet was associated with lower HbA1c, blood pressure and CHD risk and supports a role for low GI fruit consumption in the management of type 2 diabetes. ClinicalTrials.gov NCT00438698 The Canadian Institutes of Health Research; Canada Research Chair Endowment of the Federal Government of Canada, Loblaw Companies, and Barilla (Italy). The online version of this article (doi:10.1007/s00125-010-1927-1) contains supplementary material, which is available to authorised users.
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影响因子：
168.9
作者：
HERTOG, MGL;FESKENS, EJM;KROMHOUT, D
通讯作者：
KROMHOUT, D
影响因子：
7.1
作者：
Hertog, MGL;Sweetman, PM;Kromhout, D
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Kromhout, D
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Jenkins, David J. A.;Kendall, Cyril W. C.;Leiter, Lawrence A.
通讯作者：
Leiter, Lawrence A.
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作者：
CRAPO, PA;KOLTERMAN, OG;HENRY, RR
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HENRY, RR