Neural correlates of top-down letter processing.
Neural correlates of top-down letter processing.
复制标题
自上而下字母处理的神经关联
DOI：
10.1016/j.neuropsychologia.2009.10.024
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发表时间：
2010-01
期刊：
影响因子：
2.6
通讯作者：
Tian J
中科院分区：
文献类型：
--
作者：
Liu J;Li J;Zhang H;Rieth CA;Huber DE;Li W;Lee K;Tian J
本研究采用功能磁共振成像（fMRI）研究了自上而下的字母加工与错觉字母检测任务。参与者回答是否在一个非常嘈杂的图像中存在许多不同的可能的字母之一。在最初的训练变得越来越困难之后，他们继续检测字母，即使图像由纯噪声组成，这消除了强烈的自下而上输入的污染。对于虚幻的字母检测，在几个皮层区域观察到更大的fMRI激活。这些区域包括楔前叶，一个通常参与自上而下处理物体的区域，以及左侧上级顶叶小叶，一个先前被确定为处理有效字母和单词刺激的区域。此外，自上而下的字母识别还激活了左额下回，这一区域可能参与了一般自上而下的加工和字母特定自下而上的加工的整合。这些研究结果表明，这些区域可能发挥了重要作用，自上而下以及自下而上的字母和单词的处理，并可能有互惠功能连接到更后的区域在单词和字母处理网络。
This fMRI study investigated top-down letter processing with an illusory letter detection task. Participants responded whether one of a number of different possible letters was present in a very noisy image. After initial training that became increasingly difficult, they continued to detect letters even though the images consisted of pure noise, which eliminated contamination from strong bottom-up input. For illusory letter detection, greater fMRI activation was observed in several cortical regions. These regions included the precuneus, an area generally involved in top-down processing of objects, and the left superior parietal lobule, an area previously identified with the processing of valid letter and word stimuli. In addition, top-down letter detection also activated the left inferior frontal gyrus, an area that may be involved in the integration of general top-down processing and letter-specific bottom-up processing. These findings suggest that these regions may play a significant role in top-down as well as bottom up processing of letters and words, and are likely to have reciprocal functional connections to more posterior regions in the word and letter processing network.
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