Effects of Dietary Yucca Schidigera Extract and Oral Candida utilis on Growth Performance and Intestinal Health of Weaned Piglets.
Effects of Dietary Yucca Schidigera Extract and Oral Candida utilis on Growth Performance and Intestinal Health of Weaned Piglets.
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日粮丝兰提取物和口服产朊假丝酵母对断奶仔猪生长性能和肠道健康的影响
DOI：
10.3389/fnut.2021.685540
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发表时间：
2021
影响因子：
5
通讯作者：
Tang Z
中科院分区：
文献类型：
--
作者：
Yang Z;Wang Y;He T;Ziema Bumbie G;Wu L;Sun Z;Sun W;Tang Z
断奶仔猪经历了从母乳到固体饲料的转变，出现了病原菌的增殖、腹泻的出现、生长性能差甚至死亡。植物提取物和益生菌在提高动物生长性能、抗氧化能力和免疫功能方面具有一定的潜力。本研究旨在探讨饲粮中添加丝兰提取物（YSE）和产朊假丝酵母（CU）对断奶仔猪生长性能和肠道健康的影响。根据2 × 2析因设计，以CU为主要因素，选用28日龄健康断奶仔猪40头，随机分为4组，每组10头：（1）基础日粮+0.85%生理盐水（CON）组;（2）基础日粮+0.85%生理盐水（CON）组;（2）仔猪饲喂基础日粮，口服1 mL 1 × 109 cfu/mL C.试验组仔猪在基础日粮中添加120 mg/kg的YSE，同时灌胃1 mL的0.85%生理盐水（YSE），试验组仔猪在基础日粮中添加120 mg/kg的YSE，同时灌胃1 mL的1 × 109 cfu/mL的C.在0.85%盐水中的utilis（YSE+CU）。本研究为期28天，旨在评价日粮YSE和口服CU对断奶仔猪生长性能、免疫力、抗氧化功能、回肠形态和肠道菌群的影响。日粮YSE可提高断奶仔猪的日增重、脾脏指数、淋巴结指数、血清GLU、BUN、T-SOD、T-AOC、CAT浓度、回肠绒毛高度和绒毛高度/隐窝深度、空肠闭合蛋白、β-definsin-2浓度和回肠闭合蛋白浓度降低腹泻率、死亡率、直肠pH值、尿pH值、BUN、MDA浓度、隐窝深度（P < 0.05），改善盲肠菌群多样性。口服CU可提高仔猪ADG、ADFI、T-SOD、T-AOC、CAT活性、回肠绒毛高度、绒毛高度/隐窝深度、空肠occludin、β-definsin-2含量（P <0. 05），降低腹泻率、死亡率、尿pH、BUN、MDA含量、隐窝深度（P <0. 05），改善盲肠菌群多样性。结果表明，YSE和CU可提高仔猪T-SOD、T-AOC、CAT活性、绒毛高度/隐窝深度、空肠occludin浓度，降低断奶仔猪腹泻率28%，降低胃pH、回肠pH、盲肠pH、尿液pH、MDA、隐窝深度，改善盲肠菌群多样性。YSE和CU可提高断奶仔猪的生长性能，降低腹泻率，改善肠道健康，增加盲肠菌群的多样性和丰富度，有望作为抗生素替代饲料添加剂应用于断奶仔猪生产。
Weaning piglets experienced the transformation from breast milk to solid feed and present the proliferation of pathogens, the presence of diarrhea, poor growth performance and even death. Plant extracts and probiotics have certain potential in improving animal growth performance, antioxidant capacity and immune function. The purpose of this study was to explore the effects of dietary yucca schidigera extract (YSE) and oral Candida utilis (CU) on growth performance and intestinal health weaned piglets. According to a 2 × 2 factorial design with the main factors being CU (orally administered 1 mL of 0.85% saline with or without CU; fed basal diet with or without 120 mg/kg YSE), forty 28 d healthy weaned piglets were randomly allocated into four groups of 10 barrows each: (1) piglets fed basal diet and orally administered 1 mL of 0.85% saline (CON); (2) piglets fed basal diet and orally administered 1 mL 1 × 109 cfu/mL C. utilis in 0.85% saline (CU); (3) piglets fed the basal diet containing YSE (120 mg/kg) and orally administered 1 mL of 0.85% saline (YSE); (4) Piglets fed the basal diet containing 120 mg/kg YSE and 1 mL 1 × 109 cfu/mL C. utilis in 0.85% saline (YSE+CU). This study lasted 28 days and evaluated the effects of dietary YSE and oral CU on growth performance, immunity, antioxidant function, ileal morphology, and intestinal microflora in weaned piglets. Dietary YSE increased ADG, the spleen and lymph node indexes, serum GLU, BUN, T-SOD, T-AOC, CAT concentrations, ileal villus height and villus height/crypt depth, jejunal occludin, and β-definsin-2 concentrations and ileal occludin concentration in weaned piglets (P < 0.05); decreased the diarrhea rate and mortality, rectal pH and urine pH, the BUN and MDA concentrations, crypt depth (P < 0.05); improved the diversity of cecal microflora. Orally CU increased ADG, and ADFI, the T-SOD, T-AOC, and CAT activity, ileal villus height, villus height/crypt depth, jejunum occludin, and β-definsin-2 concentrations (P < 0.05); reduced the diarrhea rate and mortality, urine pH, the BUN and MDA concentrations, crypt depth (P < 0.05); improved the diversity of cecal microflora. Dietary YSE and orally CU increased the T-SOD, T-AOC, and CAT activity, villus height/crypt depth, jejunal occludin concentration; reduced the diarrhea rate of weaned piglets by 28%, gastric pH, ileal pH, cecal pH and urine pH, MDA, crypt depth; improved the diversity of cecal microflora. YSE and CU could improve the growth performance, reduce the diarrhea rate, improve intestinal health, and increase the diversity and abundance of cecal microflora in weaned piglets and expected to be used as antibiotics alternative feed additives in the production of weaned piglets.
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影响因子：
1.3
作者：
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通讯作者：
Dritz, Steve S.
影响因子：
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作者：
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影响因子：
2
作者：
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影响因子：
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通讯作者：
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影响因子：
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作者：
Alagawany, M. M.;Farag, M. R.;Dhama, K.
通讯作者：
Dhama, K.