A randomized controlled trial of the dissemination of an mHealth intervention for improving health outcomes: the WiseApp for Spanish-speakers living with HIV study protocol.
A randomized controlled trial of the dissemination of an mHealth intervention for improving health outcomes: the WiseApp for Spanish-speakers living with HIV study protocol.
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DOI：
10.1186/s12889-023-17538-y
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发表时间：
2024-01-17
影响因子：
4.5
通讯作者：
Schnall, Rebecca
中科院分区：
文献类型：
--
作者：
Olaya, Felix;Brin, Maeve;Caraballo, Pamela Baez;Halpern, Mina;Jia, Haomiao;Ramirez, Sergio Ozoria;Padilla, Janeth Juarez;Stonbraker, Samantha;Schnall, Rebecca
关键词：
虽然艾滋病毒无法治愈，但坚持抗逆转录病毒疗法可以延长艾滋病毒感染者的寿命，提高其生活质量。尽管近年来全球艾滋病毒感染率有所下降，但纽约市和多米尼加共和国的拉罗马纳继续报告拉丁裔人口的高感染率。在这些地理热点地区，许多艾滋病毒感染者仍然没有受到病毒抑制，这表明需要采取额外的干预措施来克服药物依从性障碍。量身定制和文化上适当的移动的健康（mHealth）技术可以成为提高依从性的一种吸引人的方式。这项试验的主要目的是测试移动健康工具的有效性，以改善生活在纽约市和多米尼加共和国的西班牙语人群的艾滋病毒药物治疗依从性。WiseApp研究是一项在纽约和多米尼加共和国的248名艾滋病毒感染者中进行的为期12个月的双臂随机对照试验。参与者被随机分配到与WiseApp（干预）或标准护理（对照）相关联的CleverCap药瓶。所有参与者在基线、3个月、6个月和12个月随访时完成调查，研究小组在每个研究时间点通过抽血获得HIV-1病毒载量和CD 4计数结果。近年来，使用移动医疗技术来改善艾滋病毒感染者的药物依从性已经得到实施。虽然一些研究发现短期内抗逆转录病毒治疗的依从性有所改善，但关于这些干预措施如何改善西班牙语人口依从性的信息有限。纽约市拉丁美洲人的艾滋病毒感染率不成比例，这表明在接触和治疗这一群体方面存在不公平的做法。由于缺乏针对拉丁裔人群的移动健康研究，以及为西班牙语使用者量身定制的应用程序，WiseApp研究不仅将证明这种特定移动健康应用程序的有效性，而且还将为整个移动健康研究社区做出贡献。本试验于2022年5月31日在Clinicaltrials.gov（NCT 05398185）注册。
While there is no cure for HIV, adherence to antiretroviral therapy can extend the lifespan and improve the quality of life of people with HIV. Despite the global reduction of HIV infection rates in recent years, New York City and La Romana, Dominican Republic, continue to report high infection rates among Latino populations. Many people with HIV remain virally unsuppressed in these geographic hotspots, suggesting a need for additional interventions to overcome medication adherence barriers. Tailored and culturally appropriate mobile health (mHealth) technology can be an engaging way to improve adherence. The primary objective of this trial is to test the effectiveness of an mHealth tool to improve HIV medication adherence among Spanish-speaking people living in New York City and the Dominican Republic. The WiseApp study is a two-arm randomized controlled trial among 248 people with HIV across the New York and Dominican Republic sites over the course of 12 months. Participants are randomly assigned to either receive a CleverCap pill bottle that is linked to the WiseApp (intervention) or standard of care (control). All participants complete surveys at baseline, 3-month, 6-month, and 12-month follow-up visits and the study team obtains HIV-1 viral load and CD4 count results through blood draw at each study timepoint. The use of mHealth technologies to improve medication adherence among people with HIV has been implemented in recent years. Although some studies have found improvement in adherence to antiretroviral therapy in the short term, there is limited information about how these interventions improve adherence among Spanish-speaking populations. Disproportionate rates of HIV infection among Latinos in New York City suggest an existing inequitable approach in reaching and treating this population. Due to a lack of mHealth studies with Latino populations, and apps tailored to Spanish-speakers, the WiseApp study will not only demonstrate the effectiveness of this particular mHealth app but will also contribute to the mHealth research community as a whole. This trial was registered with Clinicaltrials.gov (NCT05398185) on 5/31/2022.
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影响因子：
4.4
作者：
Amico KR;Lindsey JC;Hudgens M;Dallas R;Horvath KJ;Dunlap A;Goolsby R;Johnson MM;Heckman B;Crawford J;Secord E;Purswani M;Reirden D;Rathore M;Robinson LG;Gaur AH;TERA Study Team
通讯作者：
TERA Study Team
DOI：
10.1515/ijamh-2020-0054
发表时间：
2020-08-27
影响因子：
--
作者：
Stonbraker S;Haight E;Soriano L;Guijosa L;Davison E;Bushley D;Messina L;Halpern M
通讯作者：
Halpern M
影响因子：
1.7
作者：
Ranjit YS;Krishnan A;Ghosh D;Cravero C;Zhou X;Altice FL
通讯作者：
Altice FL
DOI：
10.1016/j.ijmedinf.2018.11.012
发表时间：
2019-02-01
影响因子：
4.9
作者：
Beauchemin, Melissa;Gradilla, Melissa;Schnall, Rebecca
通讯作者：
Schnall, Rebecca
影响因子：
4.5
作者：
Flynn G;Jia H;Reynolds NR;Mohr DC;Schnall R
通讯作者：
Schnall R