Targeted single-shot methods for diffusion-weighted imaging in the kidneys.
Targeted single-shot methods for diffusion-weighted imaging in the kidneys.
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DOI：
10.1002/jmri.22556
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发表时间：
2011-06
影响因子：
4.4
通讯作者：
Larson, Andrew C.
中科院分区：
文献类型：
--
作者：
Jin, Ning;Deng, Jie;Zhang, Longjiang;Zhang, Zhuoli;Lu, Guangming;Omary, Reed A.;Larson, Andrew C.
探讨将内容积成像（IVI）技术与单次激发扩散加权（DW）自旋回波回波平面成像（SE-EPI）和DW-SPLICE（快速自旋回波分割采集）序列结合用于肾脏DW成像的可行性。采用单次激发DW-SE-EPI、DW-SPLICE、靶向DW-SE-EPI和靶向DW-SPLICE对10名健康志愿者进行肾脏DW成像。我们比较了这些靶向DW-SE-EPI和靶向DW-SPLICE方法与常规全FOV DW-SE-EPI和DW-SPLICE测量在体模和正常志愿者中的定量扩散测量精度和图像质量。与全FOV DW-SE-EPI和DW-SPLICE方法相比，在体模和志愿者研究中，靶向DW-SE-EPI和靶向DW-SPLICE方法产生的图像具有上级整体质量，伪影较少，失真较少，空间模糊减少。用四种方法中的每一种测量的ADC值是相似的，并且与先前发表的数据一致。单次激发DW-SE-EPI、靶向DW-EPI和靶向DW-SPLICE在肾皮质和髓质中的ADC值和体素内非相干运动（IVIM）测量值之间无统计学显著差异（p > 0.05）。与全FOV DW成像方法相比，靶向DW-SE-EPI和靶向DW-SPLICE技术减少了单次激发DW-SE-EPI图像中观察到的图像失真和伪影，减少了DW-SPLICE图像中的模糊，并产生了与传统全FOV方法产生的定量DW和IVIM测量结果相当的定量DW和IVIM测量结果。
To investigate the feasibility of combining the inner-volume-imaging (IVI) technique with single-shot diffusion-weighted (DW) spin-echo echo-planar imaging (SE-EPI) and DW-SPLICE (split acquisition of fast spin-echo) sequences for renal DW imaging. Renal DW imaging was performed in 10 healthy volunteers using single-shot DW-SE-EPI, DW-SPLICE, targeted-DW-SE-EPI and targeted-DW-SPLICE. We compared the quantitative diffusion measurement accuracy and image quality of these targeted-DW-SE-EPI and targeted DW-SPLICE methods with conventional full FOV DW-SE-EPI and DW-SPLICE measurements in phantoms and normal volunteers. Compared with full FOV DW-SE-EPI and DW-SPLICE methods, targeted-DW-SE-EPI and targeted-DW-SPLICE approaches produced images of superior overall quality with fewer artifacts, less distortion and reduced spatial blurring in both phantom and volunteer studies. The ADC values measured with each of the four methods were similar and in agreement with previously published data. There were no statistically significant differences between the ADC values and intra-voxel incoherent motion (IVIM) measurements in the kidney cortex and medulla using single-shot DW-SE-EPI, targeted-DW-EPI and targeted-DW-SPLICE (p > 0.05). Compared with full-FOV DW imaging methods, targeted-DW-SE-EPI and targeted-DW-SPLICE techniques reduced image distortion and artifacts observed in the single-shot DW-SE-EPI images, reduced blurring in DW-SPLICE images and produced comparable quantitative DW and IVIM measurements to those produced with conventional full-FOV approaches.
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影响因子：
3.3
作者：
Schick, F
通讯作者：
Schick, F
影响因子：
4.4
作者：
Finsterbusch, Juergen
通讯作者：
Finsterbusch, Juergen
影响因子：
3.3
作者：
NORRIS, DG;BORNERT, P;LEIBFRITZ, D
通讯作者：
LEIBFRITZ, D
影响因子：
3.3
作者：
Griswold, MA;Jakob, PM;Haase, A
通讯作者：
Haase, A
影响因子：
3.3
作者：
Reese, TG;Heid, O;Wedeen, VJ
通讯作者：
Wedeen, VJ